Skin antiseptic composition dispenser and methods of use

Abstract

Skin antiseptic composition dispensers and methods of use are disclosed. The skin antiseptic composition dispenser may include a container with one or more walls that are substantially impermeable to ethylene oxide gas during normal ethylene oxide sterilization processes. In some embodiments, the container may include flexible walls free of metallic foil barrier layers. The containers may also include one or more vents in addition to one or more openings used to dispense the skin antiseptic composition within the container. The dispenser may include an applicator with a hydrophilic foam.

1 - 15 . (canceled) 
     
     
         16 . A skin antiseptic composition dispenser comprising:
 a container defining an interior volume,   skin antiseptic composition located within the interior volume of the container; and   dispensing means for dispensing the skin antiseptic composition;   wherein the container comprises
 a first layer impermeable to liquid and vapor phases of the skin antiseptic composition having an interior surface adjacent the skin antiseptic composition; 
 a barrier layer that is substantially impermeable to gaseous ethylene oxide, and 
 an adhesive adhering the barrier layer to at least a portion of an exterior surface of the first layer; 
   wherein the first layer and the barrier layer each independently comprise one or more polymeric walls free of metallic foil layers.   
     
     
         17 . The dispenser according to  claim 16 , wherein the barrier layer covers less than 100% of the first layer. 
     
     
         18 . The dispenser according to  claim 17 , wherein the barrier layer covers at least 60% of the first layer. 
     
     
         19 . The dispenser of  claim 18 , wherein the adhesive layer comprises a pressure sensitive adhesive. 
     
     
         20 . The dispenser of  claim 19 , wherein the pressure sensitive adhesive comprises and acrylic based adhesive. 
     
     
         21 . The dispenser of  claim 19 , wherein the pressure sensitive adhesive comprises an elastomer selected from the group consisting of natural rubber, and synthetic rubbers comprising polymers and/or copolymers of styrene, butadiene, acrylonitrile, isoprene and isobutylene. 
     
     
         22 . The dispenser according to  claim 18 , wherein the skin antiseptic composition comprises an agent selected from the group consisting of iodine, an iodine complex, chlorhexidine, triclosan, octenidine and combinations thereof. 
     
     
         23 . The dispenser of  claim 22 , wherein the iodine complex comprises an iodophor. 
     
     
         24 . The dispenser of  claim 22 , wherein the chlorhexidine comprises a chlorhexidine salt. 
     
     
         25 . The dispenser of  claim 24 , wherein the chlorhexidine salt is selected from the group consisting of chlorhexidine digluconate and chlorhexidine diacetate. 
     
     
         26 . The dispenser according to  claim 18 , wherein the first layer and the barrier layer are flexible. 
     
     
         27 . The dispenser according to  claim 18 , wherein the container is cylindrical.