US2012190110A1PendingUtilityA1
Immunological uses of immunomodulatory compounds for vaccine and anti-infectious disease therapy
Est. expirySep 1, 2025(expired)· nominal 20-yr term from priority
Inventors:Justin Blake BartlettGeorge W. MullerPeter SchaferChristine GalustianAngus DalgleishBrendan Meyer
A61P 35/02A61P 33/00A61P 37/04A61P 31/20A61P 37/00A61P 31/10A61P 35/00A61P 37/08A61P 31/12A61P 31/04A61P 1/16A61K 31/4035A61K 2039/55511A61K 39/39Y02A50/30
42
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Abstract
Methods of enhancing immune response to an immunogen in a subject are disclosed. Also disclosed are methods of reducing the sensitivity to an allergen in a subject. The methods comprise the administration of an immunomodulatory compound in specific dosing regimens that result in enhanced immune response or reduced sensitivity.
Claims
exact text as granted — not AI-modified1 . A method of reducing or inhibiting the immuno-suppressive activity of a regulatory T cell comprising contacting the regulatory T cell with an immunomodulatory compound for a time sufficient for the reduction or inhibition of such suppressive activity.
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