US2012196816A1PendingUtilityA1

Method for enhancing nutrient absorption with astragalosides

48
Assignee: LIN HANG-CHINGPriority: Jun 23, 2005Filed: Apr 11, 2012Published: Aug 2, 2012
Est. expiryJun 23, 2025(expired)· nominal 20-yr term from priority
A61P 3/02A61P 3/00A61P 1/00A61K 36/481A61K 31/704
48
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Claims

Abstract

The present application relates to a method for enhancing absorption of a nutrient in a subject in need thereof with an effective amount of an isolated astragaloside compound.

Claims

exact text as granted — not AI-modified
1 - 27 . (canceled) 
     
     
         28 . A method for enhancing absorption of folate in a subject in need thereof, comprising:
 identifying a human subject in need of enhanced absorption of folate, and   administering to the subject an effective amount of an isolated astragaloside compound for facilitating transportation of folate across gut cells of the subject, wherein the subject is an elderly, a pregnant woman, a nursing mother, or a patient having insomnia, depression, a cardiovascular disease, or long-term pressure.   
     
     
         29 . The method of  claim 28 , wherein the astragaloside compound is an astragaloside compound of Formula (A): 
       
         
           
           
               
               
           
         
         wherein R 1  is selected from the group consisting of H, OH, O-acetyl, O-xylopyranosyl, O-(2-acetylxylopyranosyl), O-(3-acetylxylopyranosyl), O-(2,3-diacetylxylopyranosyl), O-(2,4-diacetylxylopyranosyl), O-xylopyranosyl-(1-2)-β-D-glucopyranosyl, and O-xylopyranosyl-(1-2)-α-arabinopyranosyl; R 2  is selected from the group consisting of H, OH, O-acetyl, O-glucopyranosyl, and O-xylopyranosyl; R 3  is selected from the group consisting of H, OH, and O-acetyl; and R 4  is selected from the group consisting of 
       
       
         
           
           
               
               
           
         
       
     
     
         30 . The method of  claim 29 , wherein the astragaloside compound is selected from the group consisting of astragaloside I of Formula I: 
       
         
           
           
               
               
           
         
         astragaloside II of Formula II: 
       
       
         
           
           
               
               
           
         
         astragaloside III of Formula III: 
       
       
         
           
           
               
               
           
         
         astragaloside IV of Formula IV: 
       
       
         
           
           
               
               
           
         
         isoastragaloside I of Formula V: 
       
       
         
           
           
               
               
           
         
         astragaloside VI of Formula VI: 
       
       
         
           
           
               
               
           
         
         isoastragaloside II of Formula VII: 
       
       
         
           
           
               
               
           
         
         cycloastragenol-6-O-β-D-glucopyranose of Formula VIII

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