System for preparing a medical fluid and method for preparing a medical fluid

Abstract

A concentrate container for preparing a medical fluid, preferably for preparing a dialysis solution, is provided, the concentrate container including at least two concentrate compartments, wherein at least one of the concentrate compartments has a medical fluid outlet, and at least one of the concentrate compartments has a diluent inlet. Further, systems for preparing a medical fluid and a method for preparing a medical fluid are described.

1 . A concentrate container for preparing a medical fluid, preferably for preparing
 a dialysis solution, the concentrate container ( 10 ;  20 ;  30 ;  40 ;  50 ;  60 ;  70 ) comprising   at least two concentrate compartments ( 12 ,  14 ;  22 ,  24 ;  33 ,  34 )   wherein   at least one of the concentrate compartments has a medical fluid outlet ( 16 ;  26 ;  36 ;  46 ), and   at least one of the concentrate compartments has a diluent inlet ( 18 ;  28 ;  38 ;  48 ).   
     
     
         2 . The concentrate container of  claim 1 ,
 wherein a first concentrate compartment ( 22 ) and a second concentrate compartment ( 24 ) of the concentrate compartments are separated from each other by permanent barrier means ( 25 ), and each of the first and second concentrate compartments has a diluent inlet ( 28 ) and a medical fluid outlet ( 26 );   or   wherein a first concentrate compartment ( 33 ) and a second concentrate compartment ( 34 ) of the concentrate compartments are separated from each other by releasable barrier means ( 35 ), the first concentrate compartment has a diluent inlet ( 18 ) and the second concentrate compartment has a medical fluid outlet ( 16 ).   
     
     
         3 . The concentrate container of  claim 1 , wherein
 a first concentrate compartment ( 32 ) and a second concentrate ( 33 ) compartment of the concentrate compartments are separated from each other by permanent barrier means ( 25 ), and each of the first and second concentrate compartments has a diluent inlet ( 18 ) and the first concentrate compartment has a medical fluid outlet ( 16 ); and   a third concentrate compartment ( 34 ) of the concentrate compartments is separated from the second concentrate compartment ( 33 ) by releasable barrier means ( 35 ) and has a medical fluid outlet ( 16 ).   
     
     
         4 . The concentrate container of  claim 1 ,
 wherein the at least one medical fluid outlet ( 16 ) and the at least one diluent inlet ( 18 ) are separate from each other; and/or   wherein the concentrate container has an angled or V-shaped inner surface ( 19 ); and/or   wherein the concentrate container has an angled or V-shaped inner surface ( 19 ) and is adapted such that it is positionable and operable having the angle of the angled or V-shaped surface at the bottom; and/or   wherein the concentrate container has at least one fluid transmission means ( 49 ); and/or   wherein one or more of the medical fluid outlets ( 16 ) is each fluidly connected to a long channel ( 150 ) having at least one outlet ( 160 ;  160   a ,  160   b ); and/or   wherein the concentrate container ( 302 ) has a channel ( 150 ) being fluidly connected to one or more of the medical fluid outlets ( 16 ) and having at least one outlet ( 160 ;  160   a ,  160   b ); and/or   wherein the concentrate container ( 303 ) includes a first channel ( 150   a ) being fluidly connected to one of the medical fluid outlets ( 16 ) and having an outlet ( 160   a ), and a second channel ( 150   b ) being fluidly connected to another one of the medical fluid outlets ( 16 ) and having another outlet ( 160   b ), wherein the first and the second channels ( 150   a ,  150   b ) are fluidly separated by separating means ( 313 ).   
     
     
         5 . The concentrate container of  claim 1 ,
 wherein the first concentrate compartment includes at least one restrictor means ( 52 ) or at least one restrictor means subdividing the first concentrate compartment into sub-compartments ( 53 ,  54 ); and/or   wherein the concentrate container includes at least one filter means ( 55 ) provided at the at least one medical fluid outlet and/or at the at least one diluent inlet;   and/or   wherein the concentrate container includes a lid ( 61 ) or a sealable lid, adapted to close at least one of the concentrate compartments.   
     
     
         6 . The concentrate container of  claim 1 ,
 wherein at least two different components of a concentrate are provided in different concentrate compartments;   and/or   wherein one of the concentrate compartments includes glucose;   and/or   wherein the at least two different concentrate components include at least one element chosen from sodium bicarbonate, sodium chloride, magnesium chloride, potassium chloride, calcium chloride, and citric acid;   and/or   wherein a first component of a concentrate includes sodium bicarbonate and sodium chloride; a second component of the concentrate includes sodium chloride, magnesium chloride×6H 2 O, potassium chloride, calcium chloride×6H 2 O, and anhydrous citric acid; and a third component of the concentrate includes glucose×H 2 O;   and/or   wherein a first component of a dry concentrate includes 187.5 g sodium bicarbonate and 327.5 g sodium chloride; a second component of the dry concentrate includes 35 g sodium chloride, 6.1 g magnesium chloride×6H 2 O, 8.95 g potassium chloride, 13.2 g calcium chloride×6H 2 O, and 11.5 g anhydrous citric acid; and a third component of the dry concentrate includes 66 g glucose×H 2 O.   
     
     
         7 . Fluid container system for preparing a medical fluid, preferably for preparing
 a dialysis solution, comprising   a fluid container ( 110 ) for collecting a prepared medical fluid, the fluid container having a medical fluid drainage line ( 111 ,  1111 ), and   another fluid container ( 120 ) for collecting a consumed medical fluid, the fluid container ( 110 ) being insertable into the another fluid container ( 120 ).   
     
     
         8 . The system of  claim 7 , wherein at least one element chosen from the fluid container ( 110 ) and the another fluid container ( 120 ) is a flexible container, a disposable, a bag, a bag having a gusset ( 71 ) on each side and/or a bag having a bottom including two outwardly bendable folds ( 72 ); and/or
 wherein the medical fluid drainage line ( 111 ) and/or the another fluid container each include a tube ( 111 ;  121 ) extending into the interior or to the bottom of the respective fluid container; and/or   wherein the fluid container includes at least one first line connection means ( 1140 ;  1140   a ,  1140   b ) for at least one fluid transfer line ( 114 ) and a second line connection means ( 1111 ) which is connectable to, connected to or included in the medical fluid drainage line ( 111 ); and/or   wherein the another fluid container includes at the tube a third line connection means ( 1221 ) for a consumed medical fluid collection line ( 122 ).   
     
     
         9 . Kit of parts for preparing a medical fluid, comprising at least two elements chosen from a concentrate container ( 10 ;  20 ;  30 ;  40 ;  50 ;  60 ;  70 ) according to  claim 1 , a fluid container ( 110 ), a fluid container system ( 110 ,  120 ) comprising a fluid container ( 110 ) for collecting a prepared medical fluid, the fluid container having a medical fluid drainage line ( 111 ,  1111 ), and another fluid container ( 120 ) for collecting a consumed medical fluid, the fluid container ( 110 ) being insertable into the another fluid container ( 120 ), and a transport means ( 200 ) adapted to support and/or to include at least one of the concentrate container, the fluid container, and the fluid container system. 
     
     
         10 . A system for preparing a medical fluid, preferably for preparing a dialysis solution, the system ( 100 ) comprising
 a concentrate container ( 10 ;  20 ;  30 ;  40 ;  50 ;  60 ;  70 ) according to  claim 1 ,   a fluid container ( 110 ) fluidly connected to a medical fluid removal line ( 112 ),   at least one fluid transfer line ( 114 ) fluidly connecting the at least one medical fluid outlet ( 16 ) of the concentrate container and the fluid container.   
     
     
         11 . The system of  claim 10 ,
 wherein the fluid container includes a medical fluid drainage line ( 111 ); and/or   wherein the system includes another fluid container connected to a consumed medical fluid collection line ( 122 ), the fluid container being insertable into the another fluid container; and/or   wherein the concentrate container has at least one fluid transmission means ( 49 ), one of the fluid transmission means being connectable or weldable to the medical fluid drainage line ( 111 ) and/or another one of the fluid transmission means being connectable or weldable to the consumed medical fluid collection line ( 122 ).   
     
     
         12 . The system of  claim 10 ,
 wherein the at least one diluent inlet ( 18 ) of the concentrate container is fluidly connected to a diluent feed line ( 118 ); and/or   wherein the fluid container and the another fluid container are the fluid container and the another fluid container of the fluid container system comprising a fluid container ( 110 ) for collecting a prepared medical fluid, the fluid container having a medical fluid drainage line ( 111 ,  1111 ), and   another fluid container ( 120 ) for collecting a consumed medical fluid, the fluid container ( 110 ) being insertable into the another fluid container ( 120 );   and/or wherein at least one of the concentrate container, the fluid container, and the fluid container system is tiltably and/or removably installed in the system.   
     
     
         13 . The system of  claim 10 ,
 wherein the concentrate container is positioned at the top or at the bottom of at least one of the fluid container and of the another fluid container; and/or   wherein the system comprises a transport means ( 200 ) adapted to support and/or to include at least one of the concentrate container, the fluid container and the another fluid container.   
     
     
         14 . The system of  claim 10 ,
 wherein the system is adapted to be a mobile and/or modular system; and/or   wherein at least two elements chosen from the concentrate container, the fluid container, the another fluid container and the transport means are modular components of the system; and/or   wherein the concentrate container is rigid; and/or wherein the fluid container and the another fluid container are flexible.   
     
     
         15 . A method comprising using a kit of parts according to  claim 9 , the concentrate container thereof and/or the fluid container system thereof in dialysis, acute dialysis, hemodialysis, hemodiafiltration, peritoneal dialysis, or for preparing a dialysis solution. 
     
     
         16 . A method for preparing a medical fluid, preferably for preparing a medical fluid or a dialysis solution in a system according to  claim 10 , the method comprising
 providing a concentrate container ( 10 ;  20 ;  30 ;  40 ;  50 ;  60 ;  70 ) including at least one concentrate compartment  12 ,  14 ), wherein a first compartment ( 12 ) of the concentrate compartments contains a first concentrate component;   feeding a diluent into the first compartment;   rinsing the first compartment by the diluent and diluting the first concentrate component; and   transferring the diluted first concentrate component into a fluid container.   
     
     
         17 . The method of  claim 16 , wherein a second compartment ( 14 ) of the concentrate compartments contains a second concentrate component;
 the method comprising   feeding the diluent into the second compartment;   rinsing the second compartment by the diluent and diluting the second concentrate component; and   transferring the diluted second concentrate component into the fluid container.   
     
     
         18 . The method of  claim 17 ,
 wherein each of the first and second compartments is separately fed with the diluent and rinsed; or   wherein the feeding and rinsing of the second compartment is performed by passing the diluent from the first compartment into the second compartment.   
     
     
         19 . The method of  claim 17 , wherein
 the concentrate container further includes a third compartment ( 34 ) containing a third concentrate component;   each of the first and second compartments ( 32 ,  33 ) is separately fed with the diluent and rinsed; and   the feeding and rinsing of the third compartment and the diluting of the third concentrate component is performed by passing the diluent from the second compartment into the third compartment.   
     
     
         20 . The method of  claim 16 ,
 wherein during feeding the diluent a first diluent is fed into the first   compartment and a second diluent is fed into the second compartment, the first diluent and the second diluent being different from each other.