Inhaler for the administration of an anticholinergic

Abstract

An inhalation kit comprising: (a) an inhaler displaying a flow resistance of about 0.01 to 0.1, √{square root over (kPa)} min/L; and (b) an inhalable powder comprising tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 to 500 μm, and a method of administering an inhalable powder containing tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 μm to 500 μm, the method comprising actuating an inhaler a flow resistance of about 0.01 to 0.1 √{square root over (kPa)} min/L containing the inhalable powder.

1 - 21 . (canceled) 
     
     
         22 . An inhaler comprising a housing containing two windows, a deck with air inlet ports and a screen secured by a screen housing, an inhalation chamber connected to the deck on which there is a push button provided with two sharpened pins and movable counter to a spring, a mouthpiece which is connected to the housing, the deck and a cover via a spindle to enable the cover to be flipped open or shut, and three holes with diameters below 1 mm in the central region of the deck around the capsule chamber and underneath the screen housing and screen. 
     
     
         23 . The inhaler according to  claim 22 , wherein a main air flow enters the inhaler between the deck and the housing near the spindle, and the deck has a reduced width in this area, which forms an entrance slit for the air flow. 
     
     
         24 . The inhaler according to  claim 22 , wherein the inhaler displays a flow resistance of 0.01-0.1 √kPa min/l. 
     
     
         25 . The inhaler according to  claim 22 ., wherein the inhaler displays a flow resistance of 0.02-0.06 √kPa min/l.