US2012213822A1PendingUtilityA1
Chemo-immunotherapy method
Est. expirySep 21, 2025(expired)· nominal 20-yr term from priority
A61K 31/00A61K 2039/545A61K 45/06A61P 35/00A61P 43/00A61K 2039/57A61K 39/0011
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Abstract
A method of treating or preventing disease, said method comprising administering to a subject, simultaneously, sequentially or separately, an antigen and a chemotherapeutic agent or agents comprising the steps of: administering the chemotherapeutic agent or agents, and administering an antigen up to 6 weeks after the chemotherapeutic agent.
Claims
exact text as granted — not AI-modified1 - 20 . (canceled)
21 . A method of treating cancer in a subject, said method comprising:
administering chemotherapy to the subject, and immunizing the subject with an antigen up to 6 weeks after the chemotherapy, wherein the antigen is 5T4 and wherein the chemotherapy is selected from the group consisting of irinotecan, fluorouracil, leucovorin, FOLFOX (5-fluorouracil, leucovorin and oxaliplatin), and IFL (irinotecan, 5-fluorouracil and leucovorin).
22 . The method of claim 21 , comprising immunizing the subject with the antigen prior to administering the chemotherapy.
23 . The method of claim 21 , comprising immunizing the subject with the antigen during a same time frame as administering the chemotherapy.
24 . A method for treating cancer in a subject, said method comprising:
administering chemotherapy to the subject; and immunizing the subject with an antigen within 48 hours after chemotherapy, wherein the antigen is 5T4.
25 . A method for treating cancer in a subject, said method comprising:
administering chemotherapy to the subject; and immunizing the subject with an antigen between 4 and 6 weeks after chemotherapy, wherein the antigen is 5T4.Cited by (0)
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