US2012213822A1PendingUtilityA1

Chemo-immunotherapy method

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Assignee: HARROP RICHARDPriority: Sep 21, 2005Filed: Feb 21, 2012Published: Aug 23, 2012
Est. expirySep 21, 2025(expired)· nominal 20-yr term from priority
A61K 31/00A61K 2039/545A61K 45/06A61P 35/00A61P 43/00A61K 2039/57A61K 39/0011
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Claims

Abstract

A method of treating or preventing disease, said method comprising administering to a subject, simultaneously, sequentially or separately, an antigen and a chemotherapeutic agent or agents comprising the steps of: administering the chemotherapeutic agent or agents, and administering an antigen up to 6 weeks after the chemotherapeutic agent.

Claims

exact text as granted — not AI-modified
1 - 20 . (canceled) 
     
     
         21 . A method of treating cancer in a subject, said method comprising:
 administering chemotherapy to the subject, and   immunizing the subject with an antigen up to 6 weeks after the chemotherapy,   wherein the antigen is 5T4 and wherein the chemotherapy is selected from the group consisting of irinotecan, fluorouracil, leucovorin, FOLFOX (5-fluorouracil, leucovorin and oxaliplatin), and IFL (irinotecan, 5-fluorouracil and leucovorin).   
     
     
         22 . The method of  claim 21 , comprising immunizing the subject with the antigen prior to administering the chemotherapy. 
     
     
         23 . The method of  claim 21 , comprising immunizing the subject with the antigen during a same time frame as administering the chemotherapy. 
     
     
         24 . A method for treating cancer in a subject, said method comprising:
 administering chemotherapy to the subject; and   immunizing the subject with an antigen within 48 hours after chemotherapy, wherein the antigen is 5T4.   
     
     
         25 . A method for treating cancer in a subject, said method comprising:
 administering chemotherapy to the subject; and   immunizing the subject with an antigen between 4 and 6 weeks after chemotherapy, wherein the antigen is 5T4.

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