Handheld processing device including medical applications for minimally and non invasive glucose measurements

Abstract

The present disclosure includes a handheld processing device including medical applications for minimally and noninvasive glucose measurements. In an embodiment, the device creates a patient specific calibration using a measurement protocol of minimally invasive measurements and noninvasive measurements, eventually creating a patient specific noninvasive glucometer. Additionally, embodiments of the present disclosure provide for the processing device to execute medical applications and non-medical applications.

1 . A handheld processing device comprising:
 an invasive glucose monitoring system;   a noninvasive glucose monitoring system, said noninvasive glucose monitoring system including one or more signal processors configured to communicate a drive signal to a light source configured to irradiate tissue of a user, said processor configured to receive one or more signals indicative of glucose in blood from at least one detector configured to detect said light after attenuation by said tissue, and configured to process said one or more signals to determine measurements of said glucose in said tissue; and   an application configured to receive glucose measurements from said invasive glucose monitoring system and said noninvasive glucose monitoring system and configured to output for display at least said glucose measurements from said invasive glucose monitoring system.   
     
     
         2 . The processing device of  claim 1 , wherein said invasive glucose monitoring system comprises a strip reader. 
     
     
         3 . The processing device of  claim 1 , comprising a communication interface. 
     
     
         4 . The processing device of  claim 3 , wherein said communication interface is configured to communicate with a data processing center to receive calibration data. 
     
     
         5 . The processing device of  claim 4 , wherein said communication interface is configured to communicate with a data processing center to send said glucose measurements. 
     
     
         6 . The processing device of  claim 1 , wherein said application is configured to instruct a user in the performance of a measurement protocol involving invasive and noninvasive measurements. 
     
     
         7 . The processing device of  claim 1 , wherein said processing device is at least a portion of a smart phone. 
     
     
         8 . The processing device of  claim 1 , wherein said application is configured to take priority use of shared resources in said processing device. 
     
     
         9 . A method of customizing a noninvasive glucometer for use by a user, the method comprising:
 electronically collecting invasive glucose measurements with a glucometer;   electronically collecting noninvasive data sets indicative of noninvasive glucose measurements with said glucometer, said data sets responsive to light attenuated by tissue of said user;   electronically storing a mapping of said noninvasive data sets to glucose values; and   providing noninvasively derived glucose measurements to said user.   
     
     
         10 . The method of  claim 9 , wherein said collecting invasive glucose measurements comprises reading a disposable strip. 
     
     
         11 . The method of  claim 9 , wherein said collecting noninvasive data sets comprises activating a light source of a noninvasive sensor, receiving signals responsive to attenuation of light from said light source by said tissue, and electronically processing said signals. 
     
     
         12 . The method of  claim 9 , wherein said storing said mapping of said noninvasive data sets comprises communicating with a remote processing device to download said mapping. 
     
     
         13 . The method of  claim 9 , wherein said storing said mapping of said noninvasive data sets comprises uploading said data sets and said invasive glucose measurements to a remote processing device. 
     
     
         14 . The method of  claim 13 , wherein said uploading includes uploading said noninvasive glucose measurements to verify operation of said glucometer. 
     
     
         15 . The method of  claim 9 , comprising executing a medical application. 
     
     
         16 . The method of  claim 9 , comprising executing a non-medical application. 
     
     
         17 . The method of  claim 16 , comprising providing cellular phone communication. 
     
     
         18 . A noninvasive glucometer, comprising:
 a memory storing a calibration; and   a front end processor driving a light source to irradiate tissue of a patient, receiving signals responsive to attenuation of said light by said tissue, processing said signals to determine one or more measurements of glucose, said processing including accessing said calibration to associate a set of data values with glucose measurements, said calibration being customized for said patient by invasive glucose measurements of said patient's tissue.   
     
     
         19 . The glucometer of  claim 18 , comprising a strip reader. 
     
     
         20 . The glucometer of  claim 18 , comprising a communication module communicating with a remote processing device to receive said calibration after said invasive glucose measurements have been acquired.