US2012245363A1PendingUtilityA1

Process for the synthesis of agomelatine

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Assignee: HARDOUIN CHRISTOPHEPriority: Aug 5, 2008Filed: Jun 1, 2012Published: Sep 27, 2012
Est. expiryAug 5, 2028(~2.1 yrs left)· nominal 20-yr term from priority
A61P 9/10A61P 37/06A61P 9/00A61P 35/00A61P 25/00A61P 25/24A61P 25/18A61P 3/00A61P 25/16A61P 25/22A61P 25/06A61P 25/20A61P 3/04A61P 25/28A61P 15/18A61P 15/10A61P 1/00C07D 209/48C07C 233/18C07C 233/11C07C 231/12C07C 233/91C07C 231/02C07C 233/08
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Claims

Abstract

Process for the industrial synthesis of the compound of formula (I)

Claims

exact text as granted — not AI-modified
1 . A compound selected from those of formula (V): 
       
         
           
           
               
               
           
         
         wherein R represents: 
       
       
         
           
           
               
               
           
         
         wherein R′ and R″, which may be the same or different, each represent a linear or branched (C 1 -C 6 )alkyl group or R′ and R″ together form a (C 2 -C 3 )alkylene chain and wherein the ring formed may be fused with a phenyl group. 
       
     
     
         2 . The compound of  claim 1 , which is 2-[2-(7-Methoxy-1-naphthyl)ethyl]-1H-isoindole-1,3(2H)-dione.

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