US2012258184A1PendingUtilityA1

Hyperlipemia-ameliorating agent, anemia-ameliorating composition, uric-acid-level-reducing composition, and food or beverage

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Assignee: KAMBAYASHI HIROAKIPriority: Dec 21, 2009Filed: Jun 20, 2012Published: Oct 11, 2012
Est. expiryDec 21, 2029(~3.4 yrs left)· nominal 20-yr term from priority
A61P 9/00A61P 3/06A61P 7/06A61P 3/00A61P 25/06A61P 27/02A61P 29/00A61P 25/00A61P 27/16A61P 3/04A61K 31/57A61P 1/10A23L 33/105A61K 31/58A61K 31/575C07J 9/00A61P 15/08C07J 17/00A61P 11/00A61K 36/258A61P 19/06A61P 13/02A23V 2002/00C07J 17/005A23L 2/52A23V 2200/332
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Claims

Abstract

A neutral-fat-level-regulating agent, a cholesterol-level-regulating agent, a free-fatty-acid-level-regulating agent or an anti-obesity agent, including: at least one of protopanaxatriol, panaxatriol, protopanaxadiol and panaxadiol which are aglycons of dammarane-type saponins; and a hyperlipemia-ameliorating agent including: at least one of the neutral-fat-level-regulating agent, the cholesterol-level-regulating agent, the free-fatty-acid-level-regulating agent and the anti-obesity agent.

Claims

exact text as granted — not AI-modified
1 . A neutral-fat-level-regulating agent, a cholesterol-level-regulating agent, a free-fatty-acid-level-regulating agent or an anti-obesity agent, comprising:
 at least one selected from the group consisting of protopanaxatriol, panaxatriol, protopanaxadiol and panaxadiol which are aglycons of dammarane-type saponins.   
     
     
         2 . The neutral-fat-level-regulating agent, the cholesterol-level-regulating agent, the free-fatty-acid-level-regulating agent or the anti-obesity agent according to  claim 1 , wherein the aglycons are derived from a strong acid-treated product obtained by treating ginseng belonging to the family Araliaceae with a strong acid. 
     
     
         3 . The neutral-fat-level-regulating agent, the cholesterol-level-regulating agent, the free-fatty-acid-level-regulating agent or the anti-obesity agent according to  claim 2 , wherein the strong acid-treated product is obtained by hydrolyzing the ginseng belonging to the family Araliaceae with an aqueous strong acid solution having a concentration of 0.01 mol/L to 4 mol/L in the presence of a lower alcohol. 
     
     
         4 . A hyperlipemia-ameliorating agent comprising:
 at least one selected from the group consisting of a neutral-fat-level-regulating agent, a cholesterol-level-regulating agent, a free-fatty-acid-level-regulating agent and an anti-obesity agent,   wherein the neutral-fat-level-regulating agent, the cholesterol-level-regulating agent, the free-fatty-acid-level-regulating agent and the anti-obesity agent each comprise at least one selected from the group consisting of protopanaxatriol, panaxatriol, protopanaxadiol and panaxadiol which are aglycons of dammarane-type saponins.   
     
     
         5 . An anemia-ameliorating composition comprising:
 panaxadiol and panaxatriol which serve as active ingredients.   
     
     
         6 . The anemia-ameliorating composition according to  claim 5 , wherein the anemia-ameliorating composition has an effect of increasing human blood hematocrit level and an effect of increasing human mean corpuscular volume level. 
     
     
         7 . The anemia-ameliorating composition according to  claim 5 , wherein the anemia-ameliorating composition is given per day in such an amount that at least 1 mg of the active ingredients is given. 
     
     
         8 . A uric-acid-level-reducing composition comprising:
 an acid-treated product residue of a plant belonging to the genus  Panax  of the family Araliaceae as an active ingredient,   wherein the acid-treated product residue is obtained by hydrolyzing the plant belonging to the genus  Panax  of the family Araliaceae in the presence of an aqueous strong acid solution and a lower alcohol and filtrating the plant with the addition of water.   
     
     
         9 . The uric-acid-level-reducing composition according to  claim 8 , wherein the plant belonging to the genus  Panax  of the family Araliaceae is  Panax notoginseng.    
     
     
         10 . The uric-acid-level-reducing composition according to  claim 8 , wherein the uric-acid-level-reducing composition is used as a blood-uric-acid-level-reducing agent, a hyperuricemia-preventing agent, a hyperuricemia-ameliorating agent, a gout-preventing agent and a gout-ameliorating agent. 
     
     
         11 . A food or beverage comprising:
 at least one selected from the group consisting of a neutral-fat-level-regulating agent, a cholesterol-level-regulating agent, a free-fatty-acid-level-regulating agent, an anti-obesity agent, a hyperlipemia-ameliorating agent, an anemia-ameliorating composition and a uric-acid-level-reducing composition,   wherein the neutral-fat-level-regulating agent, the cholesterol-level-regulating agent, the free-fatty-acid-level-regulating agent and the anti-obesity agent each comprise at least one selected from the group consisting of protopanaxatriol, panaxatriol, protopanaxadiol and panaxadiol which are aglycons of dammarane-type saponins,   wherein the hyperlipemia-ameliorating agent comprises at least one selected from the group consisting of the neutral-fat-level-regulating agent, the cholesterol-level-regulating agent, the free-fatty-acid-level-regulating agent and the anti-obesity agent,   wherein the anemia-ameliorating composition comprises panaxadiol and panaxatriol which serve as active ingredients,   wherein the uric-acid-level-reducing composition comprises an acid-treated product residue of a plant belonging to the genus  Panax  of the family Araliaceae as an active ingredient, and   wherein the acid-treated product residue is obtained by hydrolyzing the plant belonging to the genus  Panax  of the family Araliaceae in the presence of an aqueous strong acid solution and a lower alcohol and filtrating the plant with the addition of water.

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