US2012282321A1PendingUtilityA1

Wound Dressings Containing Complexes of Transition Metals and Alginate for Elastase-Sequestering

Individually held — no corporate assignee on recordPriority: Feb 29, 2000Filed: Jul 19, 2012Published: Nov 8, 2012
Est. expiryFeb 29, 2020(expired)· nominal 20-yr term from priority
A61P 43/00A61K 33/38A61L 2300/606A61L 15/44A61P 17/02A61K 31/734A61L 15/28A61L 2300/232A61K 33/34A61K 31/715A61L 2300/104A61L 2300/102
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Claims

Abstract

Transition metal (e.g., silver and copper) derivatized phosphorylated polysaccharides (cellulose, starch, gauze) provide antimicrobial and elastase sequestration properties to wound dressings, and the wound dressing have enhanced water sorption and elastase sequestration when used with alginates. Wound dressings with alginates (e.g., silver alginate, crosslinked alginates, etc.) provide enhanced wound fluid absorption as well as elastase sequestration.

Claims

exact text as granted — not AI-modified
1 - 5 . (canceled) 
     
     
         6 . A wound dressing comprising:
 a phosporylated polysaccharide substrate complexed with at least one transition metal; and   an alginate coating wherein said alginate coating is crosslinked, wherein the alginate coating comprises an alginate selected from the group consisting of ammonium alginate, sodium alginate, potassium alginate, magnesium alginate and alginic acid.   
     
     
         7 - 9 . (canceled) 
     
     
         10 . The wound dressing of  claim 6 , wherein the alginate coating comprises ammonium alginate.

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