US2012282639A1PendingUtilityA1
Light collection system
Est. expiryNov 9, 2024(expired)· nominal 20-yr term from priority
G01N 21/6428C12Q 1/66G01N 33/581G01N 21/763G01N 21/645G01N 2021/6439G01N 21/66G01N 2021/6469
57
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Claims
Abstract
The present teachings provide a detection cell for a biological material and methods for detecting biological material including a photosensitive material optically coupled to an interior volume containing the biological material so to avoid optical components or an external light source.
Claims
exact text as granted — not AI-modified1 . A detection cell for a biological material, the detection cell comprising:
an interior volume adapted to contain the biological material; and a photosensitive material optically coupled to the interior volume, the photosensitive material being adapted to detect light emitted from the biological material in the interior volume.
2 . The detection cell for biological material of claim 1 , wherein the photosensitive material forms the interior volume.
3 . The detection cell for biological material of claim 2 , further comprising a sandwich structure comprising at least two charge coupled devices, wherein the at least two charge coupled devices comprise the interior volume.
4 . The detection cell for biological material of claim 2 , the interior volume is adapted to contain a liquid or solid.
5 . The detection cell for biological material of claim 2 , wherein the photosensitive material forms an exterior layer of the interior volume.
6 . The detection cell for biological material of claim 2 , wherein the photosensitive material forms an interior layer of the interior volume.
7 . The detection cell for biological material of claim 1 , wherein the photosensitive material is part of at least one of a charge coupled device, a photodiode, and a photomultiplier tube.
8 . The detection cell 0 for biological material of claim 7 , wherein the photosensitive material is part of a channel formed around the interior volume.
9 . The detection cell for biological material of claim 18 , further comprising an avalanche breakdown system.
10 . The detection cell for biological material of claim 2 , wherein the biological material comprises at least one of chemiluminescent labeled nucleic acids and chemiluminescent labeled cells.
11 . A method for detection of a biological material, the method comprising:
transporting the biological material to an interior volume; providing a photo sensitive material optically coupled to the interior volume; emitting light from a luminescent reaction of the biological material; and detecting the light emitted from the biological material in an interior volume of the detection cell, wherein the light is emitted without an external light source.
12 . The method for detection of biological materials of claim 11 , further comprising channeling the emitted light within a waveguide.
13 . The method for detection of biological materials of claim 12 , wherein channeling the emitted light further comprises reflecting the emitted light into the interior volume.
14 . The method for detection of biological materials of claim 12 , wherein channeling the emitted light comprises refracting the emitted light in a wall of the detection cell.
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