Composition for prevention, amelioration or treatment of metabolic syndrome

Abstract

A composition comprising (a) and (b), and a food or drink or a medicine comprising the composition, wherein (a) is at least a kind of polyphenols selected from the group consisting of a polyphenol containing 15 mass % or more of proanthocyanidin having a polymerization degree of 1 to 3, hesperidin, a hesperidin derivative, and hesperetin; and (b) is at least a kind of xanthine derivatives, the mass ratio of (a):(b) in the composition being 1:(0.001 to 5), are useful for the prevention, amelioration, or treatment of metabolic syndrome, disorders of lipid metabolism (for example, fatty liver, hyperlipidemia), obesity (for example, visceral fat accumulation, subcutaneous fat accumulation), or the like.

1 . A composition for the prevention, amelioration, or treatment of metabolic syndrome, the composition comprising (a) and (b):
 (a) at least a kind of polyphenols selected from the group consisting of a polyphenol containing 15 mass % or more of proanthocyanidin having a polymerization degree of 1 to 3, hesperidin, a hesperidin derivative, and hesperetin; and   (b) at least a kind of xanthine derivatives, the mass ratio of (a):(b) in the composition being 1:(0.001 to 5).   
     
     
         2 . The composition according to  claim 1 , wherein the mass ratio of (a):(b) is 1:(0.01 to 0.5). 
     
     
         3 . The composition according to  claim 1 , wherein the xanthine derivative is caffeine, theophylline, or theobromine. 
     
     
         4 . A medicine, a food or drink, or a feed comprising the composition according to  claim 1 . 
     
     
         5 . A food or drink comprising the composition according to  claim 1 , the food or drink being labeled as at least one selected from the group consisting of improving lipid metabolism; promoting basal metabolism; reducing body weight; reducing visceral fat or subcutaneous fat; having a slimming effect; preventing or treating obesity, or ameliorating a symptom thereof; and preventing or treating metabolic syndrome, or ameliorating a symptom thereof.