Antimicrobial preservative compositions for personal care products

Abstract

A personal product antimicrobial preservative composition for preservation of topical personal care formulations is provided comprising [A] one or more undecylenic acid derivatives depicted by Formula (I), [B] one or more octanoic acid derivatives depicted by Formula (II), and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two ‘liquid alcohol ethers’; wherein, each of the two components [A] and [B] is present in the range of 5 to 20% by weight and together [A] and [B] constitute 10 to 30% by weight and the ‘liquid alcohol ether’, component [C], is present 70 to 90% by weight of the total preservative composition. A method for preserving personal care product from microbial attack is provided containing an aqueous phase comprising three component composition from about 0.5 to 2.5% by weight of the total personal care formulation.

1 . A antimicrobial preservative composition for preservation of topical personal care formulations comprising [A] one or more undecylenic acid derivatives depicted by Formula (I), wherein, M=NH—CH 2 —OH NH—CH 2 CH 2 —OH, N—(CH 2 CH 2 —OH) 2, , NHCH 2 CH 2 CH 2 N(CH 3 ) 2 , NHCH 2 CH 2 CH 2 N(CH 3 ) 2 →O, NHCH 2 CH 2 CH 2 N + (CH 3 ) 3 CH 3 SO 4   −  NHCH 2 CH 2 CH 2 N(CH 3 ) 2 CH 2 —CH 2 N + (CH 3 ) 2 —CH 2 COO −  NH—CH 2 CH 2 —CH 2 N + (CH 3 ) 2 —CH 2 (OH)CH 2 SO 2 O − , OCOR'(R′=alkyl group with C1 to C18), O—CH 2 CH 2 —OH, O—CH(OH)CH 2 —OH, O-poly-ol O—CH 2 CH 2 —OR′ (R′=undecylenoyl), O—C(CH 3 ) 2 —OH, protein (animal or vegetable derived) hydrolyzate (through nitrogen end), NH—CH 2 CH 2 —O—(O—CH 2 CH 2 ) n —CO(CH)—COONa)—CH 2 —(SO 3 Na), n=0 to 3; 
       
         
           
           
               
               
           
         
         [B] one or more octanoic acid derivatives depicted by Formula (II), wherein, M=NH—CH 2 —OH, NH—CH 2 CH 2 —OH, N—(CH 2 CH 2 —OH) 2 , or NH—CH 2 COOH; 
       
       
         
           
           
               
               
           
         
       
       and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two liquid alcohol ethers; 
       wherein, each of the two components [A] and [B] is present in the range of 5 to 20% by weight and together [A] and [B] constitute 10 to 30% by weight and the liquid alcohol ether, component [C], is present 70 to 90% by weight of the total preservative composition. 
     
     
         2 . The antimicrobial preservative composition as claimed in  claim 1 , wherein said three component preservative comprises of a mixture of
 [A] N-undecylenoyl monoethanol amide,   [B] N-octanoyl monoethanol amide and   [C] 2-phenoxy ethanol   
       and wherein, [A] and [B] together constitute 20% by weight of the preservative composition and [C] is present 80% by weight of the preservative composition. 
     
     
         3 . The antimicrobial preservative composition as claimed in  claim 1 , wherein the ‘three component’ preservative composition of antimicrobials for personal care formulations comprises of a mixture of
 [A] N-undecylenoyl monoethanol amide, 
 [B] N-octanoyl glycine and 
 [C] 2-phenoxy ethanol 
 
       wherein, [A] is present in 20% by weight and [B] is present in 10% by weight of the preservative composition and [C] is present 70% by weight of the preservative composition. 
     
     
         4 . The antimicrobial preservative composition as claimed in  claim 1 , wherein the ‘three component’ preservative compositions of antimicrobials for personal care formulations comprising a mixture of
 [A] N-undecylenoyl monoethanol amide, 
 [B] N-capryloyl glycine and 
 [C] 2-phenoxy ethanol and 2-ethyl hexyl glyceryl ether 
 
       wherein, [A] and [B] together constitute 30% by weight of the preservative composition and [C] is present 70% by weight of the preservative composition. 
     
     
         5 . The antimicrobial preservative composition as claimed in  claim 1 , wherein, the ‘three component’ preservative composition of antimicrobials for personal care formulations comprising a mixture of
 [A] N-undecylenoyl monoethanol amide, 
 [B] N-octanoyl glycine and 
 [C] 2-phenoxy ethanol 
 
       wherein [A] is 10% by weight, [B] is 7.5% by weight and [C] is present 82.5% by weight of the preservative composition. 
     
     
         6 . The antimicrobial preservative composition as claimed in  claim 1 , wherein, the ‘three component’ preservative composition of antimicrobials for personal care formulations comprising a mixture of
 [A] N-undecylenamido propyl betaine 
 [B] N-octanoyl glycine and 
 [C] 2-ethyl hexyl glyceryl ether and 2-phenoxy ethanol 
 
       wherein [A] is 10% by weight, [B] is 7.5% by weight and [C] is present 82.5% by weight of the preservative composition. 
     
     
         7 . A method for preserving personal care product from microbial attack containing an aqueous phase comprising three component composition of  claim 1  from about 0.5 to 2.5% by weight of the total personal care formulation. 
     
     
         8 . A personal care formulation for topical application comprising the antimicrobial preservative composition as claimed in  claim 1 . 
     
     
         9 . The personal care formulation as claimed in  claim 8  is selected from lotions, creams, solutions, body-washes, shampoos, serums, wipes and emulsions. 
     
     
         10 . The personal care formulations comprising the antimicrobial preservative composition as claimed in  claim 1  comprises personal care ingredients selected from the group of solvents, surfactants, emulsifiers, rheology modifiers, conditioners, emollients, skin caring ingredients, other preservatives, thickeners, lubricants, fillers, antioxidants, other preservatives, active ingredients, in particular dermatologically active ingredients, fragrances and the like as well as mixtures thereof.