US2013102535A1PendingUtilityA1

Method for Preventing Myocardial Ischemia

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Assignee: TECHNOLOGY CO LTD SHANGHAI BAJIAYI PHARMACEUTICAL SCIENCE ANDPriority: Jul 23, 2009Filed: Dec 10, 2012Published: Apr 25, 2013
Est. expiryJul 23, 2029(~3 yrs left)· nominal 20-yr term from priority
Inventors:Yaocheng RuiTiejun LiPengyuan YangYuefan Zhang
A61K 38/08A61P 9/10
47
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Claims

Abstract

Use of polypeptide micromolecule MLIF in preparing medicine for preventing and treating myocardial ischmia, where amino acid sequence of the polypeptide micromolecule MLIF is Met-Gln-Cys-Asn-Ser (SEQ ID NO:1).

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method for preventing a myocardial ischemia comprising administering to a subject in need thereof an effective amount of a MLIF peptide having the amino acid sequence of Met-Gln-Cys-Asn-Ser (SEQ ID NO:1). 
     
     
         2 . The method of  claim 1 , wherein said method prevents abnormal myocardial damage due to myocardial ischemia. 
     
     
         3 . The method of  claim 1 , wherein said method regulates an amount of creatine kinase (CK) in a normal level in blood serum of said subject. 
     
     
         4 . The method of  claim 1 , wherein said regulates an amount of lactic dehydrogenase (LDH) in a normal level in blood serum of said subject. 
     
     
         5 . The method of  claim 1 , wherein said subject is a human being. 
     
     
         6 . A pharmaceutical composition comprising a MLF peptide having the amino acid sequence of Met-Gln-Cys-Asn-Ser (SEQ ID NO:1) formulated for pharmaceutical delivery and as a medicament for preventing and treating a myocardial ischemia.

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