US2013102657A1PendingUtilityA1

Anti-angiogenic compositions and methods of use

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Assignee: HUNTER WILLIAM LPriority: Jul 19, 1993Filed: Jul 13, 2012Published: Apr 25, 2013
Est. expiryJul 19, 2013(expired)· nominal 20-yr term from priority
Inventors:William L. HunterLindsay MachanA. Arsenault
A61P 35/00A61P 43/00A61P 7/02A61P 9/00A61P 9/10A61P 9/14A61P 7/04A61P 27/02A61P 19/02A61P 13/02A61P 1/04A61P 1/16A61P 11/00A61K 31/4745A61K 9/1658A61K 38/57C08L 2203/02A61K 33/00A61K 31/555A61K 31/57C07K 14/811A61L 2300/416A61L 2300/622A61K 9/1641A61L 31/16A61L 31/145Y10S977/915A61K 9/14A61K 9/0019A61K 31/525B82Y 5/00A61K 9/0048A61K 31/136A61K 9/1647A61L 31/10A61K 31/519A61K 33/06C08L 23/0853A61K 31/426A61K 31/165A61K 9/7007Y10S977/773A61K 9/0051A61K 9/1635C07C 233/64A61K 9/5146C08L 2312/00A61L 2300/606A61K 31/203A61K 31/122A61L 2430/36C08L 29/04A61K 31/427A61K 45/06A61K 31/335A61K 9/5153A61K 31/565C08L 67/04A61K 31/337A61K 31/702A61K 9/5031A61K 33/30A61K 31/185A61K 31/20A61K 33/24
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Claims

Abstract

The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and paclitaxel. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.

Claims

exact text as granted — not AI-modified
1 .- 61 . (canceled) 
     
     
         62 . A composition comprising nanoparticles, the nanoparticles comprising an anti-angiogenic factor and a polymeric carrier. 
     
     
         63 . The composition of  claim 62 , wherein the polymeric carrier is biodegradable. 
     
     
         64 . The composition of  claim 62 , wherein the anti-angiogenic factor is paclitaxel.

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