Anti-fatigue composition, formulation and use thereof

Abstract

An anti-fatigue composition consisting of 20(S)-protopanoxadiol and lycium barbarum polysaccharide. Experiments prove that the composition exhibits a significant anti-fatigue effect. In comparison with the effect attained by the single use of lycium barbarum polysaccharide or 20(S)-protopanoxadiol, the combined use of 20(S)-protopanoxadiol and lycium barbarum polysaccharide exerts an obvious a clear synergistic effect.

1 . An anti-fatigue composition consisting of 20(S)-protopanoxadiol and  lycium barbarum  polysaccharide. 
     
     
         2 . The composition according to  claim 1 , wherein the weight ratio of the 20(S)-protopanoxadiol and  lycium barbarum  polysaccharide is 1:50 to 1:1000. 
     
     
         3 . A formulation comprising the composition according to  claim 1 , wherein the formulation consists of 20(S)-protopanoxadiol,  lycium barbarum  polysaccharide and pharmaceutically acceptable excipients. 
     
     
         4 . The formulation according to  claim 3 , wherein the formulation is in form of tablets, pills, capsules, granules or oral solution. 
     
     
         5 . A method for relieving fatigue, comprising administering the composition of  claim 1  to a subject. 
     
     
         6 . A method for relieving fatigue, comprising administering the formulation of  claim 3  to a subject. 
     
     
         7 . The method of  claim 5 , wherein the fatigue results from various causes. 
     
     
         8 . The method of  claim 7 , wherein the fatigue results from diseases. 
     
     
         9 . The method of  claim 8 , wherein the fatigue results from cancer or depression. 
     
     
         10 . (canceled) 
     
     
         11 . The composition according to  claim 1 , wherein the weight ratio of the 20(S)-protopanoxadiol and  lycium barbarum  polysaccharide is 0.01-50 to 60-480. 
     
     
         12 . The composition according to  claim 11 , wherein the weight ratio of the 20(S)-protopanoxadiol and  lycium barbarum  polysaccharide is 0.01-5 to 120-480. 
     
     
         13 . The formulation according to  claim 3 , wherein the weight ratio of the 20(S)-protopanoxadiol and  lycium barbarum  polysaccharide is 0.01-50 to 60-480. 
     
     
         14 . The formulation according to  claim 13 , wherein the weight ratio of the 20(S)-protopanoxadiol and  lycium barbarum  polysaccharide is 0.01-5 to 120-480.