Biological stent-graft

Abstract

A biological stent-graft and a method of making the same wherein a stent is surgically implanted in the lumen of an artery of a mammal, harvesting the stent-graft precursor after the stent has been incorporated into artery wall, fixing the harvested stent-graft precursor, and washing the same to yield a biological stent-graft.

1 - 40 . (canceled) 
     
     
         41 . A biological stent-graft comprising a stent made from a biologically acceptable material and a non-laminate wall of a fixed animal blood vessel subject to fixation, the stent fully incorporated and encapsulated into the wall of the fixed animal blood vessel, and the non-laminated wall of a fixed animal blood vessel an ingrowth of smooth muscle and collagen into the stent. 
     
     
         42 . The stent-graft according to  claim 41  wherein the stent is a metal stent. 
     
     
         43 . The stent-graft according to  claim 41  wherein the stent is a polymeric stent. 
     
     
         44 . The biological stent-graft of  claim 41  wherein the fixed animal blood vessel is a fixed animal arterial vessel. 
     
     
         45 . The biological stent-graft of  claim 44  wherein the fixed animal arterial vessel is a fixed canine arterial vessel. 
     
     
         46 . The biological stent-graft of  claim 44  wherein the fixed animal arterial vessel is a fixed bovine arterial vessel. 
     
     
         47 . The biological stent-graft of  claim 44  wherein the fixed animal arterial vessel is a fixed porcine arterial vessel. 
     
     
         48 . The biological stent-graft of  claim 41  wherein the stent is a self-expanding stent. 
     
     
         49 . The biological stent-graft of  claim 41  wherein the stent is an expandable stent. 
     
     
         50 . The biological stent-graft of  claim 41  wherein the fixed animal blood vessel is a glutaraldehyde fixed animal blood vessel. 
     
     
         51 . The biological stent-graft of  claim 41  wherein the fixed animal blood vessel is glycerol triglycidy ether fixed animal blood vessel. 
     
     
         52 . A biological stent-graft comprising a stent made from a biologically acceptable material and a non-laminate wall of a fixed animal blood vessel, the stent in grown in and encapsulated in the walls of the animal blood vessel, and the non-laminated wall of a fixed animal blood vessel an ingrowth of smooth muscle and collagen into the stent. 
     
     
         53 . The stent-graft according to  claim 52  wherein the stent is a metal stent. 
     
     
         54 . The stent-graft according to  claim 52  wherein the stent is a polymeric stent. 
     
     
         55 . The biological stent-graft of  claim 52  wherein the fixed animal blood vessel is a fixed animal arterial vessel. 
     
     
         56 . The biological stent-graft of  claim 55  wherein the fixed animal arterial vessel is a fixed canine arterial vessel. 
     
     
         57 . The biological stent-graft of  claim 55  wherein the fixed animal arterial vessel is a fixed bovine arterial vessel. 
     
     
         58 . The biological stent-graft of  claim 55  wherein the fixed animal arterial vessel is a fixed porcine arterial vessel. 
     
     
         59 . The biological stent-graft of  claim 52  wherein the stent is an expandable stent. 
     
     
         60 . A biological stent-graft comprising a stent made from a biological acceptable material and a non-laminate wall of a fixed and denatured animal blood vessel, the stent fully integrated into the wall of the fixed animal blood vessel.