Specimen Carrier and Method of Positioning an Organic, Biological and/or Medical Specimen

Abstract

A method of positioning an organic, biological and/or medical specimen in a desired surface region of a specimen carrier, whereby a magnet device is provided, including joining the specimen with one or a plurality of magnetic, in particular paramagnetic particles, arrangement of the magnet device relative to the specimen carrier so that a desired magnetic field arrangement is provided in a predetermined region of the specimen carrier, introduction of the specimen into the specimen carrier and arrangement of the specimen in the desired surface region with the aid of the magnet device.

We claim: 
     
         1 . Specimen carrier, comprising a structural element, wherein the structural element is formed such that an organic, biological and/or medical specimen introduced into the specimen carrier is arrangeable in a desired partial region, in particular in a desired surface region, of the specimen carrier. 
     
     
         2 . Specimen carrier according to  claim 1 , wherein the specimen carrier comprises a predetermined surface region, wherein the predetermined surface region comprises the structural element, and wherein the structural element is formed such that the introduced specimen is arranged in a desired partial region of the predetermined surface region, in particular in the desired surface region. 
     
     
         3 . Specimen carrier according to claim wherein the structural element is formed in the shape of a prominence and/or an indentation, in particular in the shape of a dome, pyramid, groove and/or depression. 
     
     
         4 . Specimen carrier according to  claim 2 , wherein the desired partial region borders the structural element or completely surrounds the structural element, in particular wherein the structural element comprises the desired partial region, in particular when the structural element is formed in the shape of a groove or a depression or comprises a groove and/or a depression. 
     
     
         5 . Specimen carrier according to  claim 1 , wherein the structural element comprises a curved surface region or an inclined plane, in particular such that the introduced specimen is directable along the curved surface region or along the inclined plane into the desired partial region. 
     
     
         6 . Specimen carrier according to claim wherein the specimen carrier comprises a bottom plate, wherein the specimen carrier lies on the bottom plate in operation, and wherein the bottom plate comprises the predetermined surface region. 
     
     
         7 . Specimen carrier according to  claim 1 , wherein the desired partial region is partially or completely planar. 
     
     
         8 . Specimen carrier according to  claim 1 , wherein the specimen carrier comprises a bottom plate and a cover plate, wherein the cover plate and the bottom plate are joined together in a manner sealed to fluids such that a cavity is formed and wherein the structural element comprises a through hole through the bottom plate or cover plate, wherein the through hole is arranged such that the specimen can be arranged in a desired partial region of the cavity. 
     
     
         9 . Specimen carrier according to  claim 1 , wherein the internal diameter of the specimen carrier is 7 mm and the structural element has a diameter of 2 mm, a radius of curvature of the top edge of 0.5 mm and a height of 1 mm. 
     
     
         10 . Specimen carrier according to  claim 1 , wherein the structural element is provided by deep drawing or hot embossing. 
     
     
         11 . Specimen carrier according to  claim 1 , wherein the specimen carrier comprises a bottom plate which comprises the structural element, in particular, wherein the bottom plate has a thickness between 1 μm and 300 μm and/or in particular wherein the structural element is provided by deep drawing or hot embossing in the bottom plate. 
     
     
         12 . Method of positioning an organic, biological and/or medical specimen in a desired surface region of the specimen carrier, comprising the steps:
 provision of a specimen carrier according to one of the preceding claims,   introduction of the specimen into the specimen carrier, and   movement of the specimen carrier so that the specimen is arranged in the desired surface region of the specimen carrier.   
     
     
         13 . Method, in particular according to  claim 12 , of positioning an organic, biological and/or medical specimen in a desired surface region of a specimen carrier, wherein the specimen carrier comprises a cavity, wherein a through hole leads into the cavity and wherein the through hole leads into the cavity from above when the specimen carrier is in operation, comprising the steps:
 filling the cavity with a first liquid;   introduction of a second liquid into the through hole, wherein the second liquid is a hydrophobic liquid; and   introduction of the specimen into the second liquid.