US2013195782A1PendingUtilityA1
Novel Glycine Derivative Capable Of Inhibiting Melanin Formation And Composition Using The Same
Est. expiryOct 22, 2030(~4.2 yrs left)· nominal 20-yr term from priority
A61K 8/44C07C 233/47A61Q 19/08C07C 237/22A61Q 19/02A61P 17/00A61K 8/30A61K 31/198
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Claims
Abstract
The invention provides a glycine derivative, having a structure shown in the following general equation (I): wherein R 1 represents a C1˜C4 alkyl group; R 2 represents a hydrogen atom or a methyl group; and n represents an integer of 1˜6.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A glycine derivative capable of inhibiting melanin formation, having a structure shown in the following general equation (I):
wherein R 1 represents a C1˜C4 alkyl group; R 2 represents a hydrogen atom or a methyl group; and n represents an integer of 1˜6.
2 . The glycine derivative according to claim 1 , wherein the glycine derivative is 3(2-acetylamino-acetylamino)-propionic acid having a structure shown in the following equation (II):
3 . The glycine derivative according to claim 1 , wherein the glycine derivative is 4-(2-Acetylamino-acetylamino)-butyric acid having a structure shown in the following equation (III):
4 . The glycine derivative according to claim 1 , wherein the glycine derivative is [(2-Acetylamino-acetyl)-methyl-amino]-acetic acid having a structure shown in the following general equation (IV):
5 . The glycine derivative according to claim 1 , wherein a solution or a buffer solution containing the glycine derivative with addition amount of 0.05˜10 wt % (weight ratio) has light transmittance more than or equal to 97% in the wavelength range of 420˜500 nm.
6 . The glycine derivative according to claim 5 , wherein the buffer solution comprises citric acid and salts thereof.
7 . The glycine derivative according to claim 5 , wherein solution or the buffer solution containing the glycine derivative with addition amount of 0.05˜10 wt % (weight ratio) has light transmittance more than or equal to 98% at the specific wavelength 440 nm.
8 . A whitening composition, comprising:
a glycine derivative with addition amount of 0.05˜10 wt % (weight ratio) wherein the glycine derivative has a function of inhibiting melanin formation and has a structure shown in the following general equation (I):
wherein R 1 represents a C1˜C4 alkyl group; R 2 represents a hydrogen atom or a methyl group; and n represents an integer of 1˜6.
9 . The composition according to claim 8 , wherein the composition comprises the glycine derivative with addition amount of 0.1˜2 wt % (weight ratio) and has a function of inhibiting melanin formation.
10 . The composition according to claim 8 , wherein the glycine derivative is 3(2-acetylamino-acetylamino)-propionic acid having a structure shown in the following general equation (II):
11 . The composition according to claim 8 , wherein the glycine derivative is 4-(2-Acetylamino-acetylamino)-butyric acid having a structure shown in the following general equation (III):
12 . The composition according to claim 8 , wherein the glycine derivative is [(2-Acetylamino-acetyl)-methyl-amino]-acetic acid having a structure shown in the following equation (IV):Join the waitlist — get patent alerts
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