US2013225489A1PendingUtilityA1

Methods for administering hypoglycemic agents

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Assignee: BUSH MARK APriority: Nov 4, 2005Filed: May 4, 2012Published: Aug 29, 2013
Est. expiryNov 4, 2025(expired)· nominal 20-yr term from priority
Inventors:Mark A. BushMary Colleen O'Neill
A61P 3/10A61P 3/04A61K 31/155A61K 31/64A61K 38/385A61K 9/0019A61K 38/26A61K 38/28A61K 31/426A61K 45/06
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Claims

Abstract

The present invention relates to methods of administering hypoglycemic agents and/or GLP-1 agonists.

Claims

exact text as granted — not AI-modified
We claim: 
     
         1 . A pharmaceutical composition suitable for subcutaneous injection via an injection device comprising a needle having a gauge of about 28 or greater comprising about 0.01 mg to about 104 mg of a polypeptide having GLP-1 agonist activity, trehalose dihydrate, mannitol, sodium phosphate, polysorbate 80, and water for injection. 
     
     
         2 . The pharmaceutical composition of  claim 1 , wherein said polypeptide having GLP-1 agonist activity comprises a polypeptide having an amino acid sequence of SEQ ID NO:1. 
     
     
         3 . The pharmaceutical composition of  claim 1 , further comprising sodium hydroxide. 
     
     
         4 . The pharmaceutical composition of  claim 1 , further comprising phosphoric acid. 
     
     
         5 . The pharmaceutical composition of  claim 1 , wherein said sodium phosphate is selected from one of the following forms: dibasic, anhydrous and monobasic, monohydrate.

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