US2013225813A1PendingUtilityA1

PROCESS FOR MAKING (R) -3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLOURO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO[2,3-d]PYRIMIDINE-4,7(3H,8H)-DIONE AND INTERMEDIATES THEREOF

46
Assignee: PROVENCAL DAVID PAULPriority: Nov 18, 2008Filed: Mar 20, 2013Published: Aug 29, 2013
Est. expiryNov 18, 2028(~2.4 yrs left)· nominal 20-yr term from priority
Inventors:David Paul ProvencalYuxin ZhaoTodd R. MillerJonathon S. Salsbury
A61P 3/10A61P 9/10A61P 37/08A61P 31/04A61P 29/00A61P 25/00A61P 27/02A61P 35/00A61P 17/06C07D 471/04A61P 17/00A61P 17/04A61P 1/04C07D 213/82A61P 1/18A61P 13/08C07C 255/23A61P 13/12A61P 19/02C07D 213/85A61P 11/06A61P 11/00
46
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The present invention relates generally intermediates for making (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A compound of formula 
       
         
           
           
               
               
           
         
         wherein G 1  is halogen. 
       
     
     
         2 . A compound of the formula 
       
         
           
           
               
               
           
         
         wherein G 1  is halogen and R 3  and R 4  are independently selected from the group consisting of hydrogen and suitable hydroxy protecting groups. 
       
     
     
         3 . A compound of the formula 
       
         
           
           
               
               
           
         
         wherein G 1  is halogen and R 3  and R 4  are independently selected from the group consisting of suitable hydroxy protecting groups. 
       
     
     
         4 . The compound of  claim 2  wherein the stereochemistry is the (R)-configuration. 
     
     
         5 . The compound of any one of  claims 1  to  3  wherein G 1  is chloro. 
     
     
         6 . The compound of  claim 2  wherein G 1  is chloro and R 3  and R 4  taken together are acetonide.

Cited by (0)

No later patents cite this yet.

References (0)

No backward citations on record.