Calibrant infusion fluid source preparation

Abstract

Methods and systems for preparation of calibrant infusion fluid sources are disclosed. In one embodiment, a precise volume of glucose is injected into a saline-solution filled calibrant infusion fluid source proximate in time to conducting a calibration procedure. The glucose concentration in the calibrant infusion fluid source is subsequently calculated based on the measured weight of the saline-solution, as determined prior to glucose injection, and the volume of glucose injected. This method provides a highly accurate and convenient manner for use in a hospital environment, for example, with an intravenous blood glucose sensor system. In another embodiment, a premixed calibrant infusion fluid source is provided that includes saline solution and a predetermined concentration of glucose. In such embodiments, shelf life problems related to water evaporation are mitigated by hermetically covering or otherwise hermetically containing the calibrant infusion fluid source up until the point of use.

What is claimed is: 
     
         1 . A method for preparing a calibrant infusion fluid source the method comprising:
 providing a calibrant infusion fluid source that includes a saline solution and a predetermined concentration of glucose;   applying a hermetic containment to the calibrant infusion fluid source and   removing the hermetic containment proximate in time to conducting a calibration procedure.   
     
     
         2 . The method of  claim 1 , wherein providing the calibrant infusion fluid source further comprises providing the calibrant infusion fluid source that includes the saline solution, the predetermined concentration of glucose and an anti-clotting agent. 
     
     
         3 . The method of  claim 2 , wherein providing the calibrant infusion fluid source further comprises providing the calibrant infusion fluid source that includes the saline solution, a predetermined concentration of glucose and heparin. 
     
     
         4 . The method of  claim 1 , wherein applying a hermetic containment further comprises wrapping the calibrant infusion fluid source in a hermetic material. 
     
     
         5 . The method of  claim 4 , wherein wrapping the calibrant infusion fluid source in a hermetic material further comprises wrapping the calibrant infusion fluid source in one of a metalized plastic or a metal foil. 
     
     
         6 . The method of any of  claim 1 , wherein applying a hermetic containment further comprises placing the calibrant infusion fluid source in a metalized bag. 
     
     
         7 . The method of  claim 6 , wherein applying a hermetic containment further comprises heat-sealing the metalized bag after placing the calibrant infusion fluid source in the metalized bag.