Systems and methods for aneurysm treatment and vessel occlusion

Abstract

A system for treating an aneurysm includes an expandable barrier positionable to bridge an aneurysm neck. The barrier may comprise a fiber mesh, a balloon or a molly anchor member, and may unroll, unfold, or inflate from a compact configuration to an expanded configuration. Expansion of the barrier may be greater radially than axially. A vaso-occlusive member comprising a coil or balloon may be deposited in the aneurysm. Another aneurysm treatment system comprises an outer fenestrated stent and/or an inner fenestrated sleeve, which may be implanted together adjacent an aneurysm neck to regulate blood flow to the aneurysm. The sleeve may be movable relative to the stent to open or occlude the fenestrations, which may vary in size, shape, and distribution. An intra-luminal vessel occlusion device comprises a stent and a sheath. A drawstring may be actuated to gradually close a sheath orifice to control blood flow through the vessel.

1 . A system comprising:
 a flexible stent configured for placement in a vessel, the stent comprising a first end and a second end and a stent wall extending therebetween defining a stent bore, the stent wall permeable to blood flow, the stent wall comprising a plurality of stent cells; and   an inner sleeve positioned inside and coaxial with the flexible stent, the inner sleeve comprising a first end and a second end and a sleeve wall extending therebetween defining a sleeve bore, the sleeve wall comprising a plurality of sleeve cells;   wherein the stent and the sleeve comprise an open configuration wherein the sleeve cells and the stent cells are aligned.   
     
     
         2 . The system of  claim 1 , wherein the stent and the sleeve comprise a closed configuration wherein the sleeve cells and the stent cells are unaligned. 
     
     
         3 . The system of  claim 2 , wherein the sleeve rotates relative to the stent to transform the system between the open configuration and the closed configuration. 
     
     
         4 . The system of  claim 3 , wherein when the system is in the open configuration the sleeve cells and stent cells comprise a plurality of windows. 
     
     
         5 . The system of  claim 4 , wherein the stent cells and sleeve cells are the same shape and size. 
     
     
         6 . They system of  claim 4 , wherein the stent cells are differently shaped and sized than the sleeve cells. 
     
     
         7 . A system comprising:
 a flexible stent configured for placement in a parent vessel, the stent comprising a first end and a second end and a stent wall extending therebetween defining a stent bore, the stent wall permeable to blood flow, the stent wall comprising a plurality of stent fenestrations, the stent further comprising a stent window located in the stent wall; and   an inner stent positioned inside and coaxial with the flexible stent, the inner stent comprising a first end and a second end and an inner stent wall extending therebetween defining an inner stent bore, the inner stent wall comprising a plurality of inner stent fenestrations.   
     
     
         8 . The system of  claim 7 , wherein the stent window is larger than the stent fenestrations. 
     
     
         9 . The system of  claim 7 , wherein the inner stent further comprises an inner stent window located in the inner stent wall. 
     
     
         10 . The system of  claim 9 , wherein the inner stent window is larger than the inner stent fenestrations. 
     
     
         11 . The system of  claim 10 , wherein the system comprises a closed configuration in which the inner stent window is offset from the stent window so that no portion of the inner stent window overlaps the stent window. 
     
     
         12 . The system of  claim 11 , wherein the system further comprises an open configuration in which the inner stent window is aligned with the stent window, forming an unimpeded opening through the stent wall and the inner stent wall. 
     
     
         13 . The system of  claim 12 , wherein the inner stent rotates relative to the stent to transform the system between the open configuration and the closed configuration. 
     
     
         14 . A system comprising:
 a flexible stent configured for placement in a vessel, the stent comprising a first end and a second end and a stent wall extending therebetween defining a stent bore, the stent wall permeable to blood flow, the stent wall comprising a plurality of stent cells, a stent window located in the stent wall;   an inner sleeve positioned inside and coaxial with the flexible stent, the inner sleeve comprising a first end and a second end and a sleeve wall extending therebetween defining a sleeve bore, the sleeve wall comprising a plurality of sleeve cells, a sleeve window located in the sleeve wall;   wherein the system comprises an open configuration in which the sleeve window is aligned with the stent window, forming an unimpeded opening through the stent wall and the sleeve wall; and   wherein the system comprises a closed configuration in which the sleeve window is offset from the stent window so that no portion of the sleeve window overlaps the stent window.   
     
     
         15 . The system of  claim 14 , wherein the sleeve cells vary in size and distribution radially and along the length of the sleeve. 
     
     
         16 . The system of  claim 14 , wherein the sleeve cells are differently shaped and sized than the stent cells. 
     
     
         17 . The system of  claim 14 , wherein the sleeve cells are the same shape and size as the stent cells. 
     
     
         18 . The system of  claim 14 , wherein the sleeve rotates relative to the stent to transform the system between the open configuration and the closed configuration.