US2013273534A1PendingUtilityA1
Socs-3 promoter methylation in cancer
Est. expirySep 5, 2023(expired)· nominal 20-yr term from priority
C12Q 1/6886C12Q 2600/154C12Q 2600/158G01N 2800/52G01N 2500/00A61P 35/00C12Q 2600/136C12Q 1/6827G01N 33/5011G01N 33/57557G01N 33/57535G01N 33/57515G01N 33/5752
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Abstract
This invention provides compositions and methods for the diagnosis and treatment of cancers that exhibit decreased SOCS-3 expression.
Claims
exact text as granted — not AI-modified1 . A method of detecting cancer in a patient, the method comprising:
determining the level of a transcript encoding SEQ ID NO:2 in a biological sample from the patient; and detecting a decrease in the level of the transcript relative to normal, thereby detecting the presence of cancer in the patient.
2 . The method of claim 1 , wherein the cancer is selected from a group consisting of lung cancer, breast cancer, mesothelioma, colon cancer, and sarcoma.
3 . The method of claim 1 , wherein the step of determining the level of the transcript comprises an amplification reaction.
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