US2013280300A1PendingUtilityA1

Polypeptides and Immunizing Compositions Containing Gram Positive Polypeptides and Methods of Use

Assignee: EPITOPIX LLCPriority: Feb 14, 2005Filed: Jul 1, 2013Published: Oct 24, 2013
Est. expiryFeb 14, 2025(expired)· nominal 20-yr term from priority
C07K 7/08C07K 16/1271C07K 16/1285C07K 2317/76C07K 14/31A61K 39/085C07K 2317/14A61K 38/00Y10S530/825A61K 38/164C07K 16/1289A61P 31/04C07K 16/1275C07K 2317/34G01N 33/56938A61K 2039/575A61K 2039/505C07K 7/06A61K 39/00
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Claims

Abstract

The present invention provides isolated polypeptides isolatable from a Staphylococcus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.

Claims

exact text as granted — not AI-modified
1 - 50 . (canceled) 
     
     
         51 . An enriched polypeptide having immunogenic activity and a mass fingerprint when digested with trypsin that includes all polypeptide fragments present in a mass fingerprint of a reference polypeptide when digested with trypsin, wherein the reference polypeptide has a molecular weight of 33 kDa as determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel and is expressed by  Staphylococcus aureus  ATCC strain 19636 when incubated in media comprising 2,2′-dipyridyl at a concentration of 1600 μM and not expressed at a detectable level when grown in the media without the 2,2′-dipyridyl.

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