US2013295648A1PendingUtilityA1

Pharmaceutical composition for treating cancer

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Assignee: KHAMAR BAKULESH MAFATLALPriority: Jan 11, 2011Filed: Jan 10, 2012Published: Nov 7, 2013
Est. expiryJan 11, 2031(~4.5 yrs left)· nominal 20-yr term from priority
Inventors:Bakulesh Mafatlal KhamarIndravadan Ambalal Modi
A61P 37/04A61P 35/00C12N 1/20A61K 39/04A61K 35/74A61K 2039/521A61K 2039/585A61K 45/06
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Claims

Abstract

The present invention relates to increase in survival of mammals suffering from desmocollin 3 expressing cancers. Mycobacterium w is administered to mammals suffering from desmocollin-3 expressing cancers. The administration of Mycobacterium w results in control of tumor and improvement in survival. Mycobacterium w can also be used along with other therapeutic agent(s)/modalities as per the requirement. The squamous type of non small cell lung cancer is known to be desmocollin-3 expressing cancer. Other cancers also express desmocollin-3.

Claims

exact text as granted — not AI-modified
We claim: 
     
         1 .  Mycobacterium w  for use in the treatment of a desmocollin-3 expressing cancer. 
     
     
         2 .  Mycobacterium w  for use according to  claim 1 , wherein said cancer is a squamous type of non small cell lung cancer. 
     
     
         3 .  Mycobacterium w  for use according to  claim 1 , wherein cancer cells of the subject suffering from said cancer have been determined to express desmocollin-3. 
     
     
         4 .  Mycobacterium w  for use according to  claim 1 , wherein said  Mycobacterium w  increases the survival of the subject suffering from a desmocollin-3 expressing cancer. 
     
     
         5 .  Mycobacterium w  for use according to  claim 1 , wherein said  Mycobacterium w  is used in a dosage of more than 10 6  cells per dose. 
     
     
         6 .  Mycobacterium w  for use according  claim 1 , wherein said  Mycobacterium w  is used in combination with at least one other therapeutic agent or modalities. 
     
     
         7 .  Mycobacterium w  as claimed in  claim 6 , wherein said at least one other therapeutic agent or modalities is a chemotherapeutic agent.

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