US2013303790A1PendingUtilityA1

Pseudopolymorphic Forms Of A HIV Protease Inhibitor

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Assignee: JANSSEN R & D IRELANDPriority: May 16, 2002Filed: Jul 11, 2013Published: Nov 14, 2013
Est. expiryMay 16, 2022(expired)· nominal 20-yr term from priority
Inventors:Hans Wim Pieter VermeerschDaniel Joseph Christiaan ThoneLuc Donne Marie-Louise JanssensPiet Tom Bert Paul Wigerinck
A61P 31/18A61P 31/12A61P 43/00C07D 493/04
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Claims

Abstract

New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.

Claims

exact text as granted — not AI-modified
1 - 14 . (canceled) 
     
     
         15 . An ethanolate solvate of the compound (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate, in which the ratio of compound to ethanol is about 1:1.

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