Therapeutic delivery system

Abstract

Therapeutic delivery systems are provided which, in a first embodiment, contain a plurality of multiphase capsules in which first and second therapeutic agents are contained in separate phases within said multiphase capsules, and are disposed to deliver said first and therapeutic agents by at least two different delivery mechanisms.

What is claimed: 
     
         1 . A therapeutic delivery system comprising a plurality of multiphase capsules, said multiphase capsules containing first and second therapeutic agents disposed in separate phases within said multiphase capsules to deliver said first and second therapeutic agents by at least two different delivery mechanisms. 
     
     
         2 . The therapeutic delivery system of  claim 1  wherein said first therapeutic agent is delivered by a topical administration, and said second therapeutic agent is delivered by a mechanism which is not topical administration. 
     
     
         3 . The therapeutic delivery system of  claim 1  wherein said first therapeutic agent comprises one or more of: antibiotics, wound healing agents, vasodilators, coagulants, birth control drugs, cardiovascular drugs, chemotherapeutic agents, vitamins, antiviral agents, anti-microbial agents, analgesics, anti-inflammatory agents, steroidal agents, hydrocortisone, triamcinolone, non-steroidal agents, ibuprofen, naproxen, flufenamic acid, mefenamic acid, meclofenamic acid, prioxicam and felbinac, transdermal decongestants and antihistamines. 
     
     
         4 . The therapeutic delivery system of  claim 1  wherein said multiphase capsules provide at least one phase capable of reincapsulation. 
     
     
         5 . The therapeutic delivery system of  claim 1  wherein said multiphase capsules have a diameter of about 0.001 micron to about 50 microns. 
     
     
         6 . The therapeutic delivery system of  claim 1  wherein said multiphase capsules comprise a cyclodextrine, waxy material, fatty material, polymer, or a combination thereof. 
     
     
         7 . The therapeutic delivery system of  claim 1  wherein said multiphase capsules comprise a double encapsulation. 
     
     
         8 . The therapeutic delivery system of  claim 1  wherein said multiphase capsules release said first therapeutic agent, said second therapeutic agent, or both, upon a change in pH. 
     
     
         9 . The therapeutic delivery system of  claim 2  wherein said second therapeutic agent comprises a fragrance oil.