US2013310318A1PendingUtilityA1
Skin collagen production-promoting agent
Est. expiryFeb 9, 2031(~4.6 yrs left)· nominal 20-yr term from priority
A61K 2800/74A61K 8/64A61Q 19/007A61K 38/018A23L 33/17A23L 2/52A23L 2/66A23V 2002/00A23L 33/18A61K 8/676A23L 33/19A61K 38/1841A23L 33/175A61K 2800/592A61Q 19/08A61Q 19/00A61P 17/00A23L 2/02A61K 38/17A23L 1/305
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Claims
Abstract
A problem of the present invention is to provide a skin collagen production-promoting agent without safety problems. Another problem of the present invention is to provide a skin collagen production-promoting food or drink product and a skin collagen production-promoting cosmetic product containing such a substance. TGF-β and/or a TGF-β degradation product, which is acquired by degrading TGF-β with a protease such as pepsin, pancreatin, etc., are used as a skin collagen production-promoting agent or the active ingredient of a skin collagen production-promoting food or drink product and a skin collagen production-promoting cosmetic product. The aforementioned TGF-β and/or TGF-β degradation product have an effect of increasing the collagen content of the skin.
Claims
exact text as granted — not AI-modified1 . A skin collagen production-promoting agent comprising TGF-β and/or a TGF-β degradation product as an active ingredient.
2 . The skin collagen production-promoting agent according to claim 1 , wherein the TGF-β degradation product is acquired by degrading TGF-β with a protease.
3 . The skin collagen production-promoting agent according to claim 2 , wherein the protease is one or more selected from trypsin, pancreatin, chymotrypsin, pepsin, papain, kallikrein, cathepsin, thermolysin, and V8 protease.
4 . The skin collagen production-promoting agent according to claim 1 , wherein the TGF-β degradation product has an average molecular weight of 500 or more and 8,000 or less.
5 . A skin collagen production-promoting food or drink product comprising the TGF-β and/or the TGF-β degradation product according to claim 1 .
6 . A skin collagen production-promoting cosmetic product containing the TGF-β and/or the TGF-β degradation product according to claim 1 .
7 . A method of improving skin quality by oral ingestion of or application of TGF-β and/or a TGF-β degradation product.
8 . A method of improving skin quality by oral ingestion of 10 μg per day or more of TGF-β and/or a TGF-β degradation product or application thereof at 0.001 to 2 wt %.
9 . The skin collagen production-promoting agent according to claim 2 , wherein the TGF-β degradation product has an average molecular weight of 500 or more and 8,000 or less.
10 . The skin collagen production-promoting agent according to claim 3 , wherein the TGF-β degradation product has an average molecular weight of 500 or more and 8,000 or less.
11 . A skin collagen production-promoting food or drink product comprising the TGF-β and/or the TGF-β degradation product according to claim 2 .
12 . A skin collagen production-promoting food or drink product comprising the TGF-β and/or the TGF-β degradation product according to claim 3 .
13 . A skin collagen production-promoting food or drink product comprising the TGF-β and/or the TGF-β degradation product according to claim 4 .
14 . A skin collagen production-promoting food or drink product comprising the TGF-β and/or the TGF-β degradation product according to claim 9 .
15 . A skin collagen production-promoting food or drink product comprising the TGF-β and/or the TGF-β degradation product according to claim 10 .
16 . A skin collagen production-promoting cosmetic product containing the TGF-β and/or the TGF-β degradation product according to claim 2 .
17 . A skin collagen production-promoting cosmetic product containing the TGF-β and/or the TGF-β degradation product according to claim 3 .
18 . A skin collagen production-promoting cosmetic product containing the TGF-β and/or the TGF-β degradation product according to claim 4 .
19 . A skin collagen production-promoting cosmetic product containing the TGF-β and/or the TGF-β degradation product according to claim 9 .
20 . A skin collagen production-promoting cosmetic product containing the TGF-β and/or the TGF-β degradation product according to claim 10 .Cited by (0)
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