Liquid sample analyzing apparatus and liquid sample introducing apparatus

Abstract

A liquid sample introducing apparatus capable of executing a process with high reliability and high speed is realized. An injection valve includes a sample storage loop connected to a mobile phase flow passage for supplying a sample to a detector of a liquid chromatograph apparatus. A sample is sucked in a needle through a valve and a pipe by a syringe, being introduced to the sample storage loop, being supplied to the mobile phase flow passage. A washing solution from a washing solution bottle is supplied to the needle by a washing unit through the valve and the pipe to wash the inner wall of the needle. The washing solution from the washing solution bottle is supplied to a washing tank by the washing unit through the valve and a pipe to wash the external wall of the needle in the washing tank.

1 . A liquid sample introducing apparatus having a mobile phase flow passage for introducing a liquid sample into a liquid sample analyzing apparatus, comprising:
 a sample storage loop;   a needle for sucking and discharging a liquid sample;   a sample injection port into which the needle is inserted;   an accounting means for sucking a liquid sample from a sample container and for discharging a liquid sample into the sample storage loop while accounting a liquid sample;   a flow passage exchanging means for injecting a liquid sample into the mobile phase flow passage, the flow passage communicating with the sample injection port; and   a control unit for controlling the accounting means,   wherein the control unit selects at least one of a plurality of injection systems to inject a liquid sample into the mobile phase flow passage, and   the control unit controls the accounting means to change volumes of air layers in front and rear of a liquid sample to be sucked on the basis of a selected one of the injection system.   
     
     
         2 . The liquid sample introducing apparatus according to  claim 1 , wherein the control unit controls the accounting means to suck a washing solution on the basis of an amount of a liquid sample to be introduced into the mobile phase flow passage and a volume from the sample injection port to the flow passage exchanging means before the liquid sample is sucked into the needle when one part of a liquid sample sucked into the needle is injected into the mobile phase flow passage. 
     
     
         3 . The liquid sample introducing apparatus according to  claim 1 , wherein the control unit controls the accounting means to suck an air having a half volume of the air layers in front and rear of a liquid sample to be sucked before or after the liquid sample is sucked into the needle when one part of a liquid sample sucked into the needle is injected into the mobile phase flow passage. 
     
     
         4 . The liquid sample introducing apparatus according to  claim 1 , wherein the control unit controls the accounting means to suck the washing solution on the basis of a volume of a washing solution used for feeding a liquid sample to the sample storage loop, a sample introduction volume, and the volume from the sample injection port to the flow passage exchanging means before a liquid sample is sucked into the needle when all volume of a liquid sample sucked into the needle is injected into the mobile phase flow passage. 
     
     
         5 . The liquid sample introducing apparatus according to  claim 1 , wherein the control unit controls the accounting means to suck an air having a half volume of the air layers in front and rear of a liquid sample to be sucked during the needle is being moved before or after the liquid sample is sucked into the needle when all volume of a liquid sample sucked into the needle is injected into the mobile phase flow passage. 
     
     
         6 . A liquid sample introducing method for introducing a liquid sample into a liquid sample analyzing apparatus having mobile phase flow passage, comprising the steps of:
 a step for sucking a liquid sample into a needle while accounting the liquid sample by using an accounting means;   a step for discharging the liquid sample sucked in the needle into a sample storage loop while accounting the liquid sample by using the accounting means;   a step for supplying the liquid sample stored in the sample storage loop to the mobile phase flow passage;   a step for selecting at least one of a plurality of injection systems to inject a liquid sample into the mobile phase flow passage and for changing volumes of air layers in front and rear of a liquid sample to be sucked on the basis of a selected one of an injection system by a control unit controlling the accounting means.