US2014005256A1PendingUtilityA1

Formulations with anti-tumour action

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Assignee: GENTIUM SPAPriority: Sep 5, 2003Filed: Sep 6, 2013Published: Jan 2, 2014
Est. expirySep 5, 2023(expired)· nominal 20-yr term from priority
A61K 31/7088A61K 31/711A61P 43/00A61K 31/337A61K 31/195A61K 45/06A61K 31/665A61P 35/00A61K 31/17
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Claims

Abstract

Formulations with anti-tumour action containing defibrotide and at least another active ingredient as active agents.

Claims

exact text as granted — not AI-modified
1 . A formulation containing, as active agents, defibrotide and at least another active ingredient with anti-tumour action. 
     
     
         2 . A formulation according to  claim 1 , which is an aqueous solution. 
     
     
         3 . A formulation according to  claim 1 , which contains customary excipients and/or adjuvants. 
     
     
         4 . A formulation according to  claim 1 , wherein the other active ingredient with anti-tumour action is selected from paclitaxel, monocrotaline, BCNU, and/or cyclophosphamide. 
     
     
         5 . A formulation according to  claim 1 , constituted by two distinct formulations that can be administered separately, one containing defibrotide and the other containing the other active ingredient with anti-tumour action. 
     
     
         6 . A formulation according to  claim 1 , as a combined preparation for simultaneous, separate, or sequential administration. 
     
     
         7 . A formulation according to  claim 1 , wherein defibrotide is obtained by extraction from animal and/or vegetable tissues. 
     
     
         8 . A formulation according to  claim 1 , wherein defibrotide is obtained synthetically.

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