US2014031423A1PendingUtilityA1

Amino acid salts of prostaglandins

Assignee: NOVAER HOLDINGS INCPriority: Oct 29, 2008Filed: Sep 26, 2013Published: Jan 30, 2014

Est. expiryOct 29, 2028(~2.3 yrs left)· nominal 20-yr term from priority

Inventors:Mitchell A. Delong Jill Marie Sturdivant

C07C 405/0041A61K 31/5575A61K 31/165C07C 2601/08C07C 279/14C07C 229/26C07C 57/26C07C 405/0016A61P 19/10A61K 31/216

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Abstract

The present invention is directed to novel amino acid prostaglandin salts and methods of making and using them.

Claims

exact text as granted — not AI-modified

1 . Crystalline latanoprost free acid arginine salt. 
     
     
         2 . A pharmaceutical composition comprising a salt according to  claim 1  and a pharmaceutically acceptable carrier. 
     
     
         3 . A method of treating glaucoma comprising administering to a subject in need thereof an effective amount of a salt according to  claim 1 . 
     
     
         4 . A method of improving nasal patency or treating neurogenic bladder comprising administering to a subject in need thereof an effective amount of a salt according to  claim 1 . 
     
     
         5 . A method of treating osteoporosis comprising administering to a subject in need thereof an effective amount of a salt according to  claim 1 . 
     
     
         6 . A method of reducing ocular pressure comprising contacting a cell with an amount of a salt according to  claim 1  effective to reduce ocular pressure. 
     
     
         7 . The method of  claim 6 , wherein the cell is in a subject.

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