US2014046117A1PendingUtilityA1

Apparatus and method for electromagnetic treatment of plant, animal, and human tissue, organs, cells, and molecules

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Assignee: PILLA ARTHUR APriority: Dec 5, 2003Filed: Oct 21, 2013Published: Feb 13, 2014
Est. expiryDec 5, 2023(expired)· nominal 20-yr term from priority
Inventors:Arthur A. Pilla
A61N 1/40A61N 2/00A61N 2/02A61N 2/008
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Claims

Abstract

An apparatus and method for electromagnetic treatment of plants, animals, and humans comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be coupled to a target pathway structure; choosing a value of said at least one waveform parameter so that said at least waveform is configured to be detectable in said target pathway structure above background activity in said target pathway structure; generating an electromagnetic signal from said configured at least one waveform; and coupling said electromagnetic signal to said target pathway structure using a coupling device.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of modulating calcium binding to calmodulin within a target tissue using a lightweight electromagnetic treatment device, the method comprising:
 placing a lightweight applicator of an electromagnetic treatment device adjacent to a target tissue;   activating the electromagnetic treatment device so that the applicator delivers a burst of waveforms having a burst duration and a burst repetition rate which induces an a peak induced magnetic field between about 1 μT and about 20 μT and an electric field having an amplitude of less than 100 mV/cm at the target tissue, such that at least one frequency component of the induced electric field falls within the bandpass of the kinetics of the Ca/CaM pathway in the target tissue with sufficient amplitude so that the induced electric field is above background electrical activity in the Ca/CaM pathway in the target tissue.   
     
     
         2 . The method of  claim 1 , further comprising configuring the induced electric field using a mathematical model which incorporates a SNR or PSNR analysis so that at least one frequency component of the induced electric field falls within the bandpass of the kinetics Ca/CaM pathway. 
     
     
         3 . The method of  claim 1 , wherein the induced electric field has an amplitude of between about 1 μV/cm to about 100 mV/cm in the target tissue and a peak induced magnetic field less than about 20 μT, and further wherein the induced electric field comprises a burst of waveforms having a burst duration of greater than about 0.065 msec and a burst repetition rate. 
     
     
         4 . The method of  claim 1 , wherein the induced electric field has an amplitude of between about 1 μV/cm to about 100 mV/cm in the target tissue, and further wherein the induced electric field comprises a burst of waveforms having a burst duration of greater than about 0.5 msec. 
     
     
         5 . The method of  claim 1 , wherein the step of activating comprises applying a burst of waveforms repeating at a frequency of less than 100 MHz and having a duty cycle less than 1. 
     
     
         6 . The method of  claim 1 , wherein the waveforms are selected from the group of wave shapes consisting of: sinusoidal, square, chaotic, random, symmetrical, asymmetrical, half- or full-wave rectified. 
     
     
         7 . The method of  claim 1 , wherein the waveforms have a frequency of approximately 27.12 MHz. 
     
     
         8 . The method of  claim 1 , further comprising modulating the calcium binding to calmodulin in the target tissue to treat pain. 
     
     
         9 . The method of  claim 1 , further comprising the step of using at least one of standard medical therapies and non-standard medical therapies adjunctively with said electromagnetic treatment. 
     
     
         10 . The method of  claim 1 , further comprising the step of using at least one of standard physical therapies and non-standard physical therapies conjunctively with said electromagnetic treatment. 
     
     
         11 . The method of  claim 1 , further comprising the step of using said electromagnetic treatment to modulate the production and utilization of growth factors, cytokines, and regulatory substances by living cells. 
     
     
         12 . The method of  claim 1 , further comprising modulating the calcium binding to calmodulin in the target tissue to treat edema. 
     
     
         13 . The method of  claim 1 , further comprising modulating the calcium binding to calmodulin in the target tissue to modulate tissue growth and repair. 
     
     
         14 . The method of  claim 1 , further comprising the step of using said electromagnetic treatment to reduce chronic and acute pain of musculoskeletal and neural origin. 
     
     
         15 . The method of  claim 1 , further comprising the step of using said electromagnetic treatment for treatment of diabetic and pressure ulcers wherein said ulcers are chronic. 
     
     
         16 . The method of  claim 1 , further comprising the step of using said electromagnetic treatment for at least one of increasing blood flow and microvascular blood perfusion. 
     
     
         17 . The method of  claim 1 , further comprising the step of using said electromagnetic treatment for at least one of neovascularization and angiogenesis. 
     
     
         18 . The method of  claim 1 , further comprising the step of using said electromagnetic treatment to enhance immune response for malignant and benign conditions. 
     
     
         19 . The method of  claim 1 , further comprising the step of using said electromagnetic treatment to enhance transudation. 
     
     
         20 . A method of modulating the kinetics of calcium binding to calmodulin within a target tissue using a lightweight electromagnet treatment device, the method comprising:
 activating the lightweight electromagnetic treatment device to emit a burst of waveforms having a burst duration of greater than 65 μsec and a burst period of between about 0.1 to about 10 seconds;   inducing an electrical field of amplitude of less than 100 mV/cm at the target tissue to modulate the kinetics of calcium binding to calmodulin within the target tissue, wherein a at least some of the frequency components of the induced electrical field fall within the time constant of Ca/CaM binding with an amplitude sufficient so that the induced electric field is detectable above background electrical activity in the Ca/CaM pathway in the target tissue.   
     
     
         21 . The method of  claim 20 , wherein the induced electrical field is configured using a mathematical model to be detectable in the Ca/CaM target pathway above background electrical activity in the Ca/CaM target pathway. 
     
     
         22 . The method of  claim 20 , wherein the induced electrical field comprises a plurality of frequency components fall within the time constant of Ca/CaM binding with an amplitude sufficient so that the induced electric field is detectable above background electrical activity in the Ca/CaM pathway in the target tissue. 
     
     
         23 . The method of  claim 20 , further comprising placing the device adjacent to the tissue to be treated. 
     
     
         24 . The method of  claim 20 , wherein the induced electric field has an amplitude of between about 1 μV/cm to about 100 mV/cm in the target tissue, and further wherein the induced electric field comprises a burst of waveforms having a burst duration greater than about 0.5 msec. 
     
     
         25 . The method of  claim 20 , wherein the step of activating comprises applying a burst of waveforms repeating at a frequency of less than 100 MHz and having a duty cycle less than 1. 
     
     
         26 . The method of  claim 20 , wherein the waveforms are selected from the group of wave shapes consisting of: sinusoidal, square, chaotic, random, symmetrical, asymmetrical, half- or full-wave rectified. 
     
     
         27 . The method of  claim 20 , wherein the waveforms have a frequency of approximately 27.12 MHz. 
     
     
         28 . The method of  claim 20 , further comprising modulating the kinetics of calcium binding to calmodulin in the target tissue to treat pain. 
     
     
         29 . The method of  claim 20 , further comprising modulating the kinetics of calcium binding to calmodulin in the target tissue to treat edema. 
     
     
         30 . The method of  claim 20 , further comprising modulating the kinetics of calcium binding to calmodulin in the target tissue to modulate tissue growth and repair. 
     
     
         31 . A method of treating pain and edema in a target tissue using a low-power, lightweight electromagnetic treatment device, the method comprising:
 placing an applicator of the low-power, lightweight electromagnetic treatment device adjacent to the target tissue;   activating the low-power, lightweight electromagnetic treatment device to emit a burst of waveforms having a burst duration of greater than 65 μsec and a burst period of between about 0.1 and about 10 seconds;   reducing pain and edema by inducing an electrical field peak amplitude of less than 100 mV/cm at the target tissue and a magnetic field of peak amplitude of less than about 20 μT.   
     
     
         32 . The method of  claim 31 , wherein the step of placing the applicator comprises wearing the applicator adjacent to the tissue to be treated. 
     
     
         33 . The method of  claim 31 , wherein the step of placing the applicator comprises conforming a lightweight wire applicator to the target anatomy. 
     
     
         34 . The method of  claim 31 , wherein the step of activating the low-power, lightweight electromagnetic treatment device comprises emitting a burst of waveforms having a frequency less than 100 MHz. 
     
     
         35 . The method of  claim 31 , wherein the step of activating the low-power, lightweight electromagnetic treatment device comprises emitting a burst of waveforms having a burst duration greater than about 0.5 msec. 
     
     
         36 . The method of  claim 31 , further comprising continuing treatment for multiple applications of a prescribed duration. 
     
     
         37 . The method of  claim 31 , further comprising continuing treatment for a treatment duration of between about 1 minute to about 30 minutes.

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