US2014050676A1PendingUtilityA1
Method for Treating Skin with Retinoids and Retinoid Boosters
Est. expiryJun 30, 2020(expired)· nominal 20-yr term from priority
Inventors:Stewart Paton GrangerIan Richard ScottRobert Mark DonovanSusanne Tekits LobstLisa Licameli
A61Q 19/08A61K 8/4946A61K 8/498A61K 8/671A61P 17/06A61Q 19/00A61K 8/347A61K 8/361A61P 17/00A61Q 19/02A61Q 17/04A61K 8/67A61K 8/30
69
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Claims
Abstract
A skin care product comprising from about 0.001% to about 10% of a retinoid, in combination with 0.0001% to about 50% of a combination of retinoid boosters.
Claims
exact text as granted — not AI-modified1 - 7 . (canceled)
8 . A method for treating skin comprising the steps of:
(i) applying to the skin a composition comprising
(a) from 0 . 01 % to 10 % of a retinoid;
(b) at least one booster compound selected from the group consisting of quercetin, coumarin, vanillin and arachidonic acid;
(c) a cosmetically acceptable vehicle, and
(ii) treating the skin for wrinkles, psoriasis, age spots and/or discoloration.
9 . The method according to claim 8 wherein the composition further comprises an additional compound which is climbazole, linoleic acid, myristic acid, 12 -hydroxystearic acid, linseed oil, cocoyl hydroxyethyl imidazoline, phosphatidyl choline, oleyl betaine, hexanoyl sphingosine, geranyl geraniol or a mixture thereof.
10 . The method according to claim 8 wherein the composition further comprises climbazole.
11 . The method according to claim 8 wherein the skin care composition further comprises a fatty alcohol or fatty acid.
12 . The method according to claim 8 wherein the composition further comprises linseed oil, cocoyl hydroxyethyl imidazoline, phosphatidyl choline or a mixture thereof.
13 . The method according to claim 8 where the booster compound or compounds make up from about 0.0001% to 50% of the composition.
14 . The method according to claim 8 wherein the booster compound or compounds potentiate the action of retinoids by increasing conversion of retinoid to retinoic acid and further wherein the compound or compounds cause an action which is an inhibition of ARAT/LRAT activity, an enhancement of retinol dehydrogenase activity, an inhibition of retinal reductase activity, antagonistic to CRABPll binding of retinoic acid and/or an inhibition of cytochrome P450 dependent retinoic acid oxidation.
15 . The method according to claim 11 wherein the composition further comprises climbazole and the fatty alcohol is cetyl alcohol.
16 . The method according to claim 11 wherein the composition further comprises bifbnazole and the fatty alcohol is cetyl alcohol.
17 . The method according to claim 8 wherein the composition further comprises glycyrrhetinic acid.
18 . The method according to claim 8 wherein the composition further comprises famesol,
19 . The method according to claim 8 wherein the composition further comprises ursolic acid.
20 . The method according to claim 8 wherein the composition further comprises a sunscreen.
21 . The method according to claim 8 wherein the composition further comprises linoieoyl monoethanolamide, palmitamide monoethanolamide, castor oil methyl ester acid, skin lightening agent or a mixture thereof.
22 . The method according to claim 8 wherein the composition further comprises 12-hydroxystearic acid.Join the waitlist — get patent alerts
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