Pesticidal Active Mixtures Comprising Isoxazoline Compounds I

Abstract

The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one isoaxazoline compound I of the formula (I) wherein R 1 , R 2 , R 3 , R 4 , R 5 and A are defined in the description; and 2) at least one active compound II selected from a group A comprising acteylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acteylcholine receptor agonists/antagonists, chloride channel activators, juvenile hormone mimics, compounds affecting the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, inhibitors of the MET, voltage-dependent sodium channel blockers, inhibitors of the lipid synthesis and other compounds as defined in the description, in synergistically effective amounts. The invention relates further to methods and use of these mixtures for combating insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant propagation material as like seeds.

1 . A pesticidal mixture comprising
 1) at least one isoxazoline compound I of formula I:   
       
         
           
           
               
               
           
         
         wherein 
         A is 
       
       
         
           
           
               
               
           
         
         
           and wherein # denotes the bond in formula I; 
         
         R 1 , R 3  are independently from one another selected from the group consisting of hydrogen, chloro and CF 3 ; 
         R 2  is hydrogen or chloro; 
         R 4  is hydrogen or CH 3 , 
         R 5  is hydrogen, or 
         R 4  and R 5  are together a bridging 1,3-butadienyl group, which form—together with the aromatic phenylring C they are attached to—a naphtyl ring; 
         or the tautomers, enantiomers, diastereomers or salts thereof, 
         and 
         2) at least one active compound II selected from 
         A.4 a nicotinic acteylcholine receptor agonist/antagonist selected from the group consisting of nicotin, cartap hydrochloride, thiocyclam and the class of neonicotinoids consisting of acteamiprid, chlothianidin, dinotefuran, imidacloprid, nitenpyram, spinosad (allosteric agonist), spinetoram (allosteric agonist), thiacloprid, thiamethoxam and AKD-1022. 
       
     
     
         2 . The mixture according to  claim 1 , wherein the substituents of the active compound I of formula I have the following meanings:
 A is A-1, A-4 or A-6;   R 1 , R 3  are independently from one another selected from the group consisting of hydrogen, chloro and CF 3 ;   R 2  is hydrogen or chloro;   R 4  is hydrogen or CH 3 ,   R 5  is hydrogen or   R 4  and R 5  are together a bridging 1,3-butadienyl group, which form—together with the aromatic phenylring C they are attached to—a naphtyl ring;   or the tautomers, enantiomers, diastereomers or salts thereof.   
     
     
         3 . The mixture according to  claim 1 , wherein the substituents of the active compound I of formula I have the following meanings:
 A is A-1, A-4 or A-6;   R 1 , R 2 , R 3  are chloro;   R 4  is hydrogen or CH 3 ,   R 5  is hydrogen or   R 4  and R 5  are together a bridging 1,3-butadienyl group, which form—together with the aromatic phenylring C they are attached to—a naphtyl ring;   or the tautomers, enantiomers, diastereomers or salts thereof.   
     
     
         4 . The mixture according to  claim 1 , wherein the substituents of the active compound I of formula I have the following meanings:
 A is A-1, A-4 or A-6;   R 1 , R 3  are chloro;   R 2  is hydrogen;   R 4  is hydrogen or CH 3 ,   R 5  is hydrogen or   R 4  and R 5  are together a bridging 1,3-butadienyl group, which form—together with the aromatic phenylring C they are attached to—a naphtyl ring;   or the tautomers, enantiomers, diastereomers or salts thereof.   
     
     
         5 . The mixture according to  claim 1 , wherein the substituents of the active compound I of formula I have the following meanings:
 A is A-1, A-4 or A-6;   R 1 , R 3  are CF 3 ;   R 2  is hydrogen;   R 4  is hydrogen or CH 3 ,   R 5  is hydrogen or   R 4  and R 5  are together a bridging 1,3-butadienyl group, which form—together with the aromatic phenylring C they are attached to—a naphtyl ring;   or the tautomers, enantiomers, diastereomers or salts thereof.   
     
     
         6 . The mixture according to  claim 1 , wherein the substituents of the active compound I of formula I have the following meanings:
 A is A-1, A-4 or A-6;   R 1  is CF 3 ;   R 2 , R 3  are hydrogen;   R 4  is hydrogen or CH 3 ,   R 5  is hydrogen or   R 4  and R 5  are together a bridging 1,3-butadienyl group, which form—together with the aromatic phenylring C they are attached to—a naphtyl ring;   or the tautomers, enantiomers, diastereomers or salts thereof.   
     
     
         7 . The mixture according to  claim 1 , wherein at least one active compound II is selected
 within group A.4 from thiocyclam, actamiprid, chlothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, AKD-1022 or spinosad.   
     
     
         8 . The mixture according to  claim 1 , wherein at least one active compound II is clothianidin, imidacloprid or thiamethoxam. 
     
     
         9 . The mixture according to  claim 1 , comprising the active compound I of the formula I and the active compound II in a weight ratio of from 500:1 to 1:100. 
     
     
         10 . A method for protecting plants from attack or infestation by insects, acarids or nematodes comprising contacting the plant, or the soil or water in which the plant is growing, with a mixture according to  claim 1  in pesticidally effective amounts. 
     
     
         11 . A method for controlling insects, arachnids or nematodes comprising contacting an insect, acarid or nematode or their food supply, habitat, breeding grounds or their locus with a mixture according to  claim 1  in pesticidally effective amounts. 
     
     
         12 . A method as claimed in  claim 10  or  11 , wherein the mixture according  claim 1  is applied in an amount of from 5 g/ha to 2000 g/ha. 
     
     
         13 . A method for protection of plant propagation material comprising contacting the plant propagation material with a mixture of  claim 1  in pesticidally effective amounts. 
     
     
         14 . A method according to  claim 13  wherein the mixture is applied in an amount of from 0.1 g to 10 kg per 100 kg of plant propagation material. 
     
     
         15 . A method as claimed in  claim 13 , wherein the plant propagation material is/are seed(s). 
     
     
         16 . A seed treated with the mixture according to  claim 1  in an amount of from 0.1 g to 10 kg per 100 kg of seeds. 
     
     
         17 . A method for protecting animals against infestation or infection by parasites which comprises administering to the animals a parasitically effective amount of a mixture according to  claim 1  to the animal in need thereof. 
     
     
         18 . A method for treating animals infested or infected by parasites which comprises administering to the animals a parasitically effective amount of a mixture according  claim 1  to the animal in need thereof. 
     
     
         19 . A method as claimed in  claim 10  wherein the active compounds I of formula I and the active compounds II are applied simultaneously, that is jointly or separately, or in succession. 
     
     
         20 . A pesticidal or parasiticidal composition, comprising a liquid or solid carrier and a mixture according to  claim 1 .