Methods And Systems For Generating Nanoparticles

Abstract

In one aspect, the present invention provides a process for forming polymeric nanoparticles, which comprises using a static mixer to create a mixed flowing stream of an anti-solvent, e.g., by introducing a liquid anti-solvent into a static mixer, and introducing a polymer solution into the mixed flowing anti-solvent stream such that controlled precipitation of polymeric nanoparticles occurs. The nanoparticles can then be separated from the anti-solvent stream.

1 - 136 . (canceled) 
     
     
         137 . A population of polymeric nanoparticles, comprising:
 a plurality of polymeric nanoparticles having an amphiphilic co-polymer as at least one constituent,   wherein said polymeric nanoparticles exhibit an average particle size equal to or less than about 100 nm and a polydispersity index in a range of about 0.05 to about 0.1.