Artificial Intelligence System for Genetic Analysis

Abstract

The present invention provides a complete artificial intelligence system for the acquisition and analysis of nucleic acid array hybridization information. The system is divided into at least one central data processing facility and one or more user facilities, linked by encrypted network connections or similar links. Each user facility may include an optical scanning system to collect hybridization signals from a nucleic acid array, an image processing system to convert the optical data into a set of hybridization parameters, a connection to a data network, and a user interface to display, manipulate, search, and analyze hybridization information. This system reads data from a gene chip or DNA microarray, or a proteomics chip, analyzes test results based on maintained parameters, evaluates patient risk for various ailments, recommends methods of treatment, presents information to medical and/or private individuals, and notifies test participants when new treatment becomes available. The test results may be used to perform individual diagnostics, longitudinal studies, population studies, or a wide variety of statistical analyses of patient data. The automated artificial intelligence system is a real time, dynamic decision making tool that can be used not only in conjunction with a clinical analysis system, but also with the information obtained in a research and development environment. Access to this system allows the user(s) to look at both clinical and non-clinical information. Most importantly, the system is intelligent and possesses the capability to interpret the information obtained. The system presents the information primarily via a secured encrypted Web interface, such as the Internet. The information is also presented in a retrievable format, such as electronic or paper format, using various computing technologies.

1 - 24 . (canceled) 
     
     
         25 . A method for facilitating a user purchase, the user purchase based on an analysis of gene expression levels or protein expression levels of an organism, the method comprising:
 performing an analysis of an organism comprising one or both of:
 i) analyzing gene expression levels associated with at least one gene of the organism, and 
 ii) analyzing protein expression levels associated with at least one protein of the organism, 
   relating the gene expression levels or protein expression levels with a biological history of the organism,   based on the relating step performed, providing information to a user regarding one or more of:
 a) a likelihood of the organism developing a specific disease, 
 b) a detected disease of the organism, 
 c) a prognosis for the organism, 
 d) a diagnosis for the organism, and 
 e) information for recommendation of a treatment; 
   receiving an indication from the user regarding a purchase to be made based on the one or more of (a)-(e); and   facilitating placement of an order based on the received indication from the user.   
     
     
         26 . The method of  claim 25 , wherein the purchase is a purchase of a prescription drug. 
     
     
         27 . The method of  claim 25 , wherein the purchase is a purchase of a genetically modified organism (GMO). 
     
     
         28 . The method of  claim 25 , wherein the purchase is a purchase of information regarding the organism's analyzed gene expression levels or analyzed protein expression levels. 
     
     
         29 . The method of  claim 25 , further comprising:
 providing additional information to the user, the additional information comprising one or more of: market-based information, disease-based information, technology-based information, species-based information, function-based information, pathway-based information, sequence-based information, mutation-based information, cluster-based information, amplification-based information, structure-based information, and phenotype-genotype correlation.   
     
     
         30 . The method of  claim 25 , further comprising facilitating a providing of an advertisement to the user based on the placed order or the performed analysis. 
     
     
         31 . The method of  claim 25 , wherein the organism is the user. 
     
     
         32 . The method of  claim 25 , wherein the organism is a GMO. 
     
     
         33 . The method of  claim 25 , wherein the biological history comprises health history or family history. 
     
     
         34 . The method of  claim 25 , wherein performing an analysis of an organism comprises analyzing an array containing a sample from the organism. 
     
     
         35 . The method of  claim 25 , wherein the provided information is used to assess a biological state of interest, the biological state of interest comprising neoplasia, cancer, immune response, environmental stress, or nutritional condition, wherein the placement of an order is further facilitated based on the assessed biological state of interest. 
     
     
         36 . An artificial intelligence system for facilitation of a user purchase, the user purchase based on an analysis of gene expression levels or protein expression levels of an organism, said system comprising:
 a computer system that is configured to analyze said gene or protein expression information through the use of an algorithm adapted for:
 performing an analysis of an organism comprising one or both of:
 i) analyzing gene expression levels associated with at least one gene of the organism, and 
 ii) analyzing protein expression levels associated with at least one protein of the organism, 
 
 relating the gene expression levels or protein expression levels with a biological history of the organism, 
 based on the relating step performed, providing information to a user regarding one or more of:
 a) a likelihood of the organism developing a specific disease, 
 b) a detected disease of the organism, 
 c) a prognosis for the organism, 
 d) a diagnosis for the organism, and 
 e) information for recommendation of a treatment; 
 
 receiving an indication from the user regarding a purchase to be made based on the one or more of (a)-(e); and 
 facilitating placement of an order based on the received indication from the user. 
   
     
     
         37 . The artificial intelligence system of  claim 36 , wherein the purchase is a purchase of a prescription drug. 
     
     
         38 . The artificial intelligence system of claim  6 , wherein the purchase is a purchase of a genetically modified organism (GMO). 
     
     
         39 . The artificial intelligence system of  claim 36 , wherein the purchase is a purchase of information regarding the organism's analyzed gene expression levels or analyzed protein expression levels. 
     
     
         40 . The artificial intelligence system of  claim 36 , wherein the algorithm is further adapted for:
 providing additional information to the user, the additional information comprising one or more of: market-based information, disease-based information, technology-based information, species-based information, function-based information, pathway-based information, sequence-based information, mutation-based information, cluster-based information, amplification-based information, structure-based information, and phenotype-genotype correlation.   
     
     
         41 . The artificial intelligence system of  claim 36 , wherein the organism is the user. 
     
     
         42 . The artificial intelligence system of  claim 36 , wherein the organism is a GMO. 
     
     
         43 . The artificial intelligence system of  claim 36 , wherein the biological history comprises health history or family history. 
     
     
         44 . The artificial intelligence system of  claim 36 , wherein performing an analysis of an organism comprises analyzing an array containing a sample from the organism. 
     
     
         45 . The artificial intelligence system of  claim 36 , the artificial intelligence system further comprising an operations server, wherein the operations server comprises a function selected from the group consisting of order management, billing management, and order tracking. 
     
     
         46 . The artificial intelligence system of  claim 36 , wherein the provided information is used to assess a biological state of interest, the biological state of interest comprising neoplasia, cancer, immune response, environmental stress, or nutritional condition, wherein the placement of an order is further facilitated based on the assessed biological state of interest.