US2014187765A1PendingUtilityA1

Near full-genome assay of hcv drug resistance

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Assignee: UNIV LEUVEN KATHPriority: Oct 31, 2007Filed: Dec 23, 2013Published: Jul 3, 2014
Est. expiryOct 31, 2027(~1.3 yrs left)· nominal 20-yr term from priority
Inventors:Grégoire VuagniauxJean-Maurice DumontJoke SnoeckSonia Van DoorenAnne-Mieke Vandamme
C12Q 1/707
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Claims

Abstract

Assays for characterization of genotypic mutations of Hepatitis C Virus (HCV) showing a resistance to anti-HCV drugs.

Claims

exact text as granted — not AI-modified
1 - 8 . (canceled) 
     
     
         9 . A pair of primers selected from the group consisting of:
 (a) poly-A and HCV1bO F6074;   (b) HCV1bOR6312 and HCV1bOF1977;   (c) HCV1bOR3306 and HCVOF129;   (d) HCV1bIR9339 and HCV1bIF6126;   (e) HCV1bIR6282 and HCV1bIF2523;   (f) HCV1bIR2770 and HCVIF278; and combinations thereof.   
     
     
         10 . The pair of primers of  claim 9 , wherein said pair of primers is HCV1bOR6312 and HCV1bOF1977. 
     
     
         11 . The pair of primers of  claim 9 , wherein said pair of primers is HCV1bOR3306 and HCVOF129. 
     
     
         12 . The pair of primers of  claim 9 , wherein said pair of primers is HCV1bIR9339 and HCV1bIF6126. 
     
     
         13 . The pair of primers of  claim 9 , wherein said pair of primers is HCV1bIR6282 and HCV1bIF2523. 
     
     
         14 . The pair of primers of  claim 9 , wherein said pair of primers is of HCV1bIR2770 and HCVIF278. 
     
     
         15 . A kit for detecting mutations in an HCV genome, wherein said kit comprises the pair of primers of  claim 9 . 
     
     
         16 . (canceled) 
     
     
         17 . The pair of primers of  claim 9 , wherein said pair of primers consists of poly-A and HCV1bOF6074.

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