Small survival-promoting/immunomodulatory peptide for treatment of brain damage, neurodegenerative disorders, and inflammatory disorders

Abstract

A synthetic peptide sequence demonstrating neuroprotective and anti-inflammatory functions is disclosed. Methods of use for the synthetic peptide are also provided.

1 .- 3 . (canceled) 
     
     
         4 . A method for treating a patient having a neurodegenerative disorder, or disorder with an inflammatory component comprising administering to said patient a therapeutically effective amount of a CHEC-9 peptide. 
     
     
         5 . The method of  claim 4 , wherein said neurodegenerative disorder is selected from the group consisting of trauma, stroke, nonspecific anoxia, mental retardation syndromes associated with progressive neuronal degeneration, and a neurodegenerative disease. 
     
     
         6 . The method of  claim 5 , wherein said neurodegenerative disease is selected from the group consisting of Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 
     
     
         7 . The method of  claim 4 , wherein said disorder with an inflammatory component is selected from the group consisting of asthma, autoimmune disease, and allergies. 
     
     
         8 .- 10 . (canceled) 
     
     
         11 . The method of  claim 4 , wherein the CHEC-9 peptide is encoded in an isolated nucleic acid molecule. 
     
     
         12 . (canceled) 
     
     
         13 . The method of  claim 4 , wherein the nucleic acid molecule is in a plasmid. 
     
     
         14 . The method of  claim 4 , wherein nucleic acid molecule is in a vector. 
     
     
         15 . The method of  claim 4 , wherein the vector is a retroviral vector. 
     
     
         16 .- 24 . (canceled)