Novel flavonol compounds, compositions thereof and method for treating bone disorders

Abstract

Flavonol compounds, pharmaceutical compositions of the compounds and methods for treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route.

1 - 32 . (canceled) 
     
     
         33 . A compound comprising a flavonol of General Formula 1: 
       
         
           
           
               
               
           
         
         wherein R 1  is OH and R 2  is OH or H. 
       
     
     
         34 . A pharmaceutical composition comprising an effective amount of a compound of  claim 33 , and optionally one or more pharmaceutically acceptable additives, earners or diluents. 
     
     
         35 . A method of treating bone disorders in a subject comprising administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition of  claim 34 . 
     
     
         36 . The method of  claim 35  wherein the pharmaceutical composition may be administered by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route. 
     
     
         37 . A composition comprising;
 a combination of at least two compounds selected from the group consisting of K012, K058, K068 and K100, and   
       
         
           
           
               
               
           
         
         optionally one or more pharmaceutically acceptable additives, carriers or diluents. 
       
     
     
         38 . A method of treating bone disorders in a subject comprising administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition of  claim 37 . 
     
     
         39 . The method of  claim 38  wherein the pharmaceutical composition may be administered by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route.