US2014220151A1PendingUtilityA1

Stability in Vitamin and Mineral Supplements

43
Assignee: WYETH LLCPriority: Feb 15, 2007Filed: Jun 20, 2013Published: Aug 7, 2014
Est. expiryFeb 15, 2027(~0.6 yrs left)· nominal 20-yr term from priority
Inventors:Alan M. GoldbergSteven S. DillsWilliam MarkBruce SuttonChad Byerley
A61P 3/02A61K 33/34A61K 33/42A23V 2002/00A23L 33/15A61K 33/26A61K 33/00A61K 33/30A61K 31/375A61K 31/409A61K 31/525A61K 45/06A61K 33/06A61K 31/355A61K 31/07A61K 31/59A61K 31/519A61K 31/4415A61K 33/32A61K 31/51A61K 31/455A23L 33/16A61K 31/197A23L 5/41
43
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The invention provides a multivitamin and mineral nutritional supplement composition comprising at least one polyvalent metal and at least one oxidizable vitamin with substantially improved resistance to reactions that lead to darkening and/or spotting and reactions that may reduce the potency of oxidizable vitamins. The composition is a multivitamin and mineral composition comprising at least one polyvalent metal and at least one oxidizable vitamin wherein the composition is substantially free of mobile bound water. The invention also includes methods for making such a composition and methods of preventing or reducing oxidation, improving the stability of oxidizable vitamins, and stabilizing the disintegration time of a multi-vitamin and mineral nutritional supplement composition.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A multivitamin and mineral composition comprising at least one polyvalent metal and least one oxidizable vitamin, wherein the composition is substantially free of mobile bound water. 
     
     
         2 . The multivitamin and mineral composition of  claim 1 , wherein the polyvalent metal is selected from the group consisting of iron, magnesium, zinc, selenium, copper, cobalt, manganese, molybdenum, vanadium, nickel, tin, chromium and combinations thereof. 
     
     
         3 . The multivitamin and mineral composition of  claim 1 , wherein the oxidizable vitamin is selected from the group consisting of Vitamin C, Vitamin E, Vitamin A, Vitamin A precursors. Vitamin B6, Vitamin D3, Vitamin K, folic Acid and combinations thereof. 
     
     
         4 . The multivitamin and mineral composition of  claim 1 , further comprising anhydrous dicalcium phosphate. 
     
     
         5 . The multivitamin and mineral composition of  claim 1 , further comprising a carotinoid. 
     
     
         6 . The multivitamin and mineral composition of  claim 1 , wherein the composition is in a solid dosage form. 
     
     
         7 . A multivitamin and mineral composition of  claim 6 , wherein the solid dosage form is selected from the group consisting of tablets, caplets, capsules, chewable dosage forms, powder, sachet and combination thereof. 
     
     
         8 . A method for reducing oxidation induced spotting in a in a multivitamin and mineral tablet and for stabilizing disintegration behavior of multivitamin and mineral tablets over time comprising: combining at least one polyvalent metal selected from the group consisting of iron, magnesium, zinc, selenium, copper, cobalt, manganese, molybdenum, vanadium, nickel, tin, chromium and combinations thereof, and at least one oxidizable vitamin selected from the group consisting of Vitamin C, Vitamin E, Vitamin A, Vitamin A precursors, Vitamin B6, Vitamin D3, folic acid and combinations thereof to form a composition, wherein the composition is substantially free of mobile bound water; and forming the composition into tablets. 
     
     
         9 . The method of  claim 8 , further comprising combining anhydrous dicalcium phosphate with the at least one polyvalent metal and at least one oxidizable vitamin. 
     
     
         10 . A multivitamin and mineral composition comprising at least 150 mg of elemental calcium per dosage unit, at least one polyvalent metal, and at least one oxidizable vitamin, wherein the composition is substantially free of mobile bound water. 
     
     
         11 . The multivitamin and mineral composition of  claim 10 , wherein the polyvalent metal is selected from the group consisting of iron, magnesium, zinc, selenium, copper, cobalt, manganese, molybdenum, vanadium, nickel, tin, chromium and combinations thereof. 
     
     
         12 . The multivitamin and mineral composition of  claim 10 , wherein the oxidizable vitamin is selected from the group consisting of Vitamin C, Vitamin E, Vitamin A, Vitamin A precursors, Vitamin B6, Vitamin D3, Vitamin K, folic acid and combinations thereof. 
     
     
         13 . The multivitamin and mineral composition of  claim 12 , wherein the oxidizable vitamin is Vitamin C. 
     
     
         14 . The multivitamin and mineral composition of  claim 10 , wherein the composition is in a solid dosage form. 
     
     
         15 . The multivitamin and mineral composition of  claim 14 , wherein the solid dosage form is selected form the group consisting of tablets, caplets, capsules, chewable dosage forms, powder, sachet and combination thereof. 
     
     
         16 . The multivitamin and mineral composition of  claim 15 , wherein the solid dosage form is a tablet. 
     
     
         17 . The multivitamin and mineral composition of  claim 10 , wherein the elemental calcium is provided in the form of anhydrous dicalcium phosphate. 
     
     
         18 . The multivitamin and mineral composition of  claim 15 , wherein a first portion of the elemental calcium is provided in the form of anhydrous dicalcium phosphate.

Join the waitlist — get patent alerts

Track US2014220151A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.