US2014235888A1PendingUtilityA1

(z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluormethylphenyl)-amide tablet formulations with improved stability

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Assignee: SANOFI SAPriority: Sep 18, 2009Filed: Apr 30, 2014Published: Aug 21, 2014
Est. expirySep 18, 2029(~3.1 yrs left)· nominal 20-yr term from priority
Inventors:Gerrit Hauck
A61P 37/00A61P 37/02A61P 7/00A61P 37/08A61P 37/06A61P 35/02A61P 35/00A61P 31/00A61P 3/02A61P 31/04A61P 29/00A61P 25/00A61P 27/02A61P 19/04A61P 19/02A61P 17/06A61P 11/02A61P 11/06A61P 17/00A61K 9/2059C07C 255/44A61K 9/2013A61K 9/2054A61K 31/277A61K 47/36A61K 9/20A61K 9/16
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Claims

Abstract

The invention relates to solid pharmaceutical compositions comprising (Z)-2-cyano-3-hydroxy-but-2-enoic acid-(4′-trifluoromethylphenyl)-amide, as well as a process for the preparation of the same, methods of using such compositions to treat subjects suffering from autoimmune diseases in particular systemic lupus erythematosus or chronic graft-versus-host disease, multiple sclerosis or rheumatoid arthritis.

Claims

exact text as granted — not AI-modified
I claim: 
     
         1 . A solid pharmaceutical composition comprising a therapeutically effective amount of teriflunomide or a pharmaceutically acceptable basic addition salt thereof, wherein the solid pharmaceutical composition does not contain colloidal silicon dioxide.

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