Method of preventing and treating hepatic disease using a2b adenosine receptor antagonists

Abstract

The invention is related to methods of preventing and treating hepatic fibrosis using A 2B adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method.

1 - 21 . (canceled) 
     
     
         22 . A method of treating viral hepatitis by administering a therapeutically effective amount of a compound having the name 3-ethyl-1-propyl-8-(1-{[3-(trifluoromethyl)phenyl]methyl}pyrazol-4-yl)-1,3,7-trihydropurine-2,6-dione and the chemical formula 
       
         
           
           
               
               
           
         
         or a pharmaceutically acceptable salt thereof. 
       
     
     
         23 . The method of  claim 22 , wherein the compound is administered orally. 
     
     
         24 . The method of  claim 22 , wherein the compound is administered by IV. 
     
     
         25 . The method of  claim 22 , wherein the mammal is human.