US2014274898A1PendingUtilityA1

Hair growth methods using fgfr3 extracellular domains

Assignee: FIVE PRIME THERAPEUTICS INCPriority: Dec 17, 2009Filed: Feb 20, 2014Published: Sep 18, 2014
Est. expiryDec 17, 2029(~3.4 yrs left)· nominal 20-yr term from priority
A61P 35/00A61K 38/179A61K 31/473C07K 14/71A61P 17/14A61Q 7/00A61K 31/506A61K 8/64
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Claims

Abstract

The present invention relates to a method of promoting hair growth comprising administering a fibroblast growth factor receptor 3 (FGFR3) extracellular domain (ECD), including native FGFR3 ECDs, variants, fragments, and fusion molecules, to a subject in an amount sufficient to promote hair growth.

Claims

exact text as granted — not AI-modified
1 .- 40 . (canceled) 
     
     
         41 . A method of promoting hair growth comprising administering an FGFR3 ECD and at least one additional agent selected from minoxidil, finasteride, and dutasteride to a subject in an amount sufficient to promote hair growth. 
     
     
         42 . A kit comprising one or more containers, wherein each container contains one or more doses of an FGFR3 ECD for promoting hair growth. 
     
     
         43 . A vector comprising a polynucleotide that encodes an FGFR3 ECD, wherein the vector is for in vivo expression of FGFR3 ECD in an animal.

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