US2014296487A1PendingUtilityA1
Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses
Est. expirySep 8, 2026(~0.2 yrs left)· nominal 20-yr term from priority
Inventors:Joseph ShefferThea NormanRichard D. DimarchiAnna-Maria A. Hays PutnamFeng TianStephanie ChuDenise KrawitzHo Sung Cho
C07K 19/00A61P 43/00C07K 14/765A61K 38/00C07K 14/62C07K 2319/00C07K 14/575C07K 14/47C07K 14/435A61P 7/00A61K 38/17
66
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Abstract
Modified human plasma polypeptides or Fc and uses thereof are provided.
Claims
exact text as granted — not AI-modified1 - 56 . (canceled)
57 . A method of modulating serum half-life or circulation time of an hPP or hA polypeptide, the method comprising substituting one or more non-naturally encoded amino acids for any one or more naturally occurring amino acids in the hPP or hA polypeptide.
58 - 75 . (canceled)
76 . A method of modulating immunogenicity of a biologically active molecule, the method comprising substituting one or more non-naturally encoded amino acids for any one or more naturally occurring amino acids in the hPP or hA polypeptide.Cited by (0)
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