US2014336250A1PendingUtilityA1

Method for treating bronchial diseases

Assignee: MICRODOSE THERAPEUTX INCPriority: Feb 22, 2002Filed: Jul 25, 2014Published: Nov 13, 2014
Est. expiryFeb 22, 2022(expired)· nominal 20-yr term from priority
A61K 31/192A61K 31/34A61K 9/0075A61K 31/341A61K 31/40A61K 9/14
65
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Claims

Abstract

Administration of a loop diuretic in nebulized dry powder form directly to a patient's lungs for treating bronchial disease.

Claims

exact text as granted — not AI-modified
1 - 9 . (canceled) 
     
     
         10 . The method of treatment according to  claim 15 , wherein the patient suffers from emphysema. 
     
     
         11 . The method of treatment according to  claim 15 , wherein the patient suffers from cystic fibrosis. 
     
     
         12 - 13 . (canceled) 
     
     
         14 . The method of treatment according to  claim 15 , wherein the patient suffers from dyspnea. 
     
     
         15 . A method for relieving a symptom of pulmonary disease in a patient suffering therefrom, wherein the pulmonary disease is selected from the group consisting of emphysema, cystic fibrosis, and dyspnea, comprising delivering directly to the patient's lungs a systemically effective amount of a non-salt formulation of furosemide and ethacrynic acid in dry powder form, wherein said systematically effective amount of a non-salt formulation is delivered as a fine powder having a particle size of 0.5-10 microns. 
     
     
         16 . The method accordingly to  claim 15 , wherein said systematically effective amount of a non-salt formulation is delivered in unit dose amounts of between about 1 and 100 milligrams. 
     
     
         17 . The method according to  claim 16 , wherein said systematically effective amount of a non-salt formulation is delivered in unit dose amounts of between about 5 and 10 milligrams. 
     
     
         18 . The method according to  claim 15 , wherein said systematically effective amount of a non-salt formulation is delivered in discrete doses as needed. 
     
     
         19 . The method according to  claim 18 , wherein said systematically effective amount of a non-salt formulation is delivered in discrete doses 1-4 times per day. 
     
     
         20 . The method according to  claim 15 , wherein said systematically effective amount of a non-salt formulation is delivered in dry powder form having a powder size of 1-6 microns.

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