US2014350041A1PendingUtilityA1

Methods and Compositions for Treating a Disease Condition in a Subject

Assignee: PALO ALTO INVESTORSPriority: Oct 15, 2004Filed: Jun 10, 2014Published: Nov 27, 2014
Est. expiryOct 15, 2024(expired)· nominal 20-yr term from priority
A61M 5/14276A61P 9/12A61N 1/36002A61N 1/05A61K 31/4188A61M 2205/054A61N 1/3605A61N 1/36117A61K 31/4168A61N 1/18A61N 1/36A61K 31/475A61K 31/395
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Claims

Abstract

Methods for treating a disease condition in a subject are provided. The subject methods are characterizing by enhancing at least one symptom of the disease condition in a manner effective to cause the subject to mount a compensatory response effective to treat the disease condition. Also provided are compositions, kits and systems for practicing the subject methods.

Claims

exact text as granted — not AI-modified
1 . A method of treating a subject for a disease condition, said method comprising:
 enhancing at least one symptom of said disease condition in a manner effective to cause said subject to mount a compensatory response effective to treat said disease condition.   
     
     
         2 . The method according to  claim 1 , wherein said enhancing comprises applying a stimulus to said subject. 
     
     
         3 . The method according to  claim 2 , wherein said stimulus is a pharmacological agent. 
     
     
         4 . The method according to  claim 2 , wherein said stimulus is an electrical stimulus. 
     
     
         5 . The method according to  claim 1 , wherein said disease condition is a manifestation of an irregularity in a homeostatic pathway. 
     
     
         6 . The method according to  claim 5 , wherein said disease condition is manifested by chronic sympathetic bias. 
     
     
         7 . The method according to  claim 6 , wherein said disease condition is a cardiovascular disease. 
     
     
         8 . The method according to  claim 7 , wherein said cardiovascular disease is hypertension. 
     
     
         9 . The method according to  claim 7 , wherein said stimulus is a pharmacological agent. 
     
     
         10 . The method according to  claim 9 , wherein said pharmacological agent is an adrenergic agonist. 
     
     
         11 - 13 . (canceled) 
     
     
         14 . The method according to  claim 1 , wherein said disease condition is an immune condition. 
     
     
         15 . The method according to  claim 14 , wherein said immune condition is asthma. 
     
     
         16 . The method according to  claim 15 , wherein said agent is a proinflammatory agent. 
     
     
         17 . The method according to  claim 1 , wherein said disease condition is an endocrine system condition. 
     
     
         18 . The method according to  claim 17 , wherein said disease condition is diabetes. 
     
     
         19 . The method according to  claim 18 , wherein said agent is an insulin blocker. 
     
     
         20 . The method according to  claim 1 , wherein said administering is of limited temporal duration. 
     
     
         21 . The method according to  claim 1 , wherein said method comprises monitoring said subject. 
     
     
         22 . The method according to  claim 21 , wherein said method comprises applying a first stimulus to said subject and monitoring said subject for a response thereto; and applying a second stimulus to said subject, wherein said second stimulus is determined based on said monitored response to said first stimulus. 
     
     
         23 - 31 . (canceled)

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