Reconstitution device

Abstract

The present invention relates to methods for reconstituting and relates to reconstitution devices suitable for reconstituting many different materials. Furthermore, the present invention includes methods of treatment and methods of use related to a reconstitution device or apparatus. Some embodiments are suitable for reconstituting small amounts of a pharmaceutical compositions and using the pharmaceutical composition for the treatment of sexual dysfunction.

We claim: 
     
         1 . A method of mixing comprising:
 filling a device with at least two compositions;   storing said at least two compositions; and   mixing said at least two compositions with said device.   
     
     
         2 . The method of  claim 1 , wherein said device comprises:
 at least one housing element capable of containing at least two compositions;   
       and
 at least one dispensing element for applying said at least two compositions. 
 
     
     
         3 . The method of  claim 1 , wherein said at least two compositions are mixed immediately prior to dispensing said at least two compositions. 
     
     
         4 . The method of  claim 1 , wherein said at least two compositions form a pharmaceutical composition. 
     
     
         5 . The method of  claim 1 , wherein the first composition of said at least two compositions is a pharmaceutically acceptable composition. 
     
     
         6 . The method of  claim 1 , wherein the first composition of said at least two compositions is a vasoactive agent. 
     
     
         7 . The method of  claim 1 , wherein a first composition of said at least two compositions is stored in a first compartment and a second composition of said at least two compositions is stored in a second compartment prior to mixing. 
     
     
         8 . The method of  claim 1 , further comprising the step of administering said at least two compositions to a subject. 
     
     
         9 . The method of  claim 4 , wherein said pharmaceutical composition is administered through a route of administration selected from a group consisting of transdermal, intranasal, buccal, and rectal. 
     
     
         10 . The method of  claim 4 , wherein the temperature of said at least two compositions is changed immediately prior to administration. 
     
     
         11 . The method of  claim 4 , wherein said at least two compositions are mixed a predetermined amount. 
     
     
         12 . The method of  claim 4 , further comprising the step of administering a pre-treatment composition contained within said device to said subject immediately prior to administration of said at least two compositions. 
     
     
         13 . The method of  claim 4 , further comprising the step of administering a post-treatment composition contained within said device to said subject immediately after administration of said at least two compositions. 
     
     
         14 . The method of  claim 13 , wherein said post-treatment composition is an anti-irritant. 
     
     
         15 . The method of  claim 1 , wherein said at least two compositions comprise at least three compositions, whereby a first composition and second composition are mixed within said device, and subsequently, a third composition is mixed with said first composition and said second composition. 
     
     
         16 . The method of  claim 8 , wherein the amount of at least two compositions administered to said subject is selected from a predetermined range. 
     
     
         17 . The method of  claim 11 , wherein mixing is limited to said predetermined amount. 
     
     
         18 . The method of  claim 1 , wherein the said at least two compositions are stored in at least three compartments and an effective dosage of a pharmaceutical composition is selected by a device user who selects which said at least two compositions are mixed. 
     
     
         19 . The method of  claim 5 , wherein the effective dose is between approximately 100 mcg and 400 mcg of alprostadil. 
     
     
         18 . The method of  claim 1 , wherein an actuator is used to select the amount of a least one composition of said at least two compositions. 
     
     
         19 . The method of  claim 1 , wherein said at least two compositions are mixed with a shearing channel. 
     
     
         20 . A method of treatment comprising:
 mixing a pharmaceutical composition for the treatment of a condition in a subject immediately prior to administration; and   administering said pharmaceutical composition to a subject,   wherein said mixing occurs in a device and said device is used for said administration of said pharmaceutical composition to said subject.   
     
     
         21 . A method of  claim 20 , wherein said condition is nail fungus. 
     
     
         22 . A method of  claim 20 , wherein said condition is male sexual dysfunction. 
     
     
         23 . A method of  claim 22 , wherein said condition is erectile dysfunction. 
     
     
         24 . A method of  claim 22 , wherein said condition is premature ejaculation. 
     
     
         25 . A method of  claim 20 , further comprising a step of administering a pre-treatment composition immediately prior to administering said pharmaceutical composition. 
     
     
         26 . A method of  claim 20 , further comprising a step of administering a post-treatment composition immediately after administering said pharmaceutical composition. 
     
     
         27 . A method of  claim 20 , wherein said condition is female sexual dysfunction. 
     
     
         28 . A method of treating sexual dysfunction comprising:
 mixing a pharmaceutical composition for the treatment of sexual dysfunction in a subject immediately prior to administration; and   administering an effect amount of said pharmaceutical composition to a subject.   
     
     
         29 . A method of  claim 20 , wherein said pharmaceutical compositions is administered by a route of administration selected from a group consisting of transdermal, intranasal, buccal, and rectal. 
     
     
         30 . A method of  claim 20 , wherein said pharmaceutical compositions is administered to the urethra and urethral meatus for male sexual dysfunction; direct vaginal and/or clitoral application for female sexual dysfunction; intraoral application of a vaccine or oral care product; intranasal application of a vaccine or medicament; intra-aural application; or ophthalmic application of a medicament. 
     
     
         31 . A method of  claim 20 , where said pharmaceutical compositions is administered by injection. 
     
     
         32 . A kit comprising:
 a device for administration; and   a pharmaceutical product for the treatment of sexual dysfunction.   
     
     
         33 . The kit of  claim 32 , further comprising a contraceptive. 
     
     
         34 . The kit of  claim 33 , wherein said contraceptive is a condom. 
     
     
         35 . The kit of  claim 32 , wherein said pharmaceutical product is for the treatment of male sexual dysfunction. 
     
     
         36 . The kit of  claim 32 , wherein said pharmaceutical product is for the treatment of female sexual dysfunction.