US2015007811A1PendingUtilityA1

Delivery devices

46
Assignee: OPTINOSE ASPriority: Nov 28, 2006Filed: Feb 3, 2014Published: Jan 8, 2015
Est. expiryNov 28, 2026(~0.4 yrs left)· nominal 20-yr term from priority
A61M 11/06A61M 15/002A61M 15/0028A61M 2202/04A61M 15/0031A61M 15/0091A61M 15/0098A61M 15/08A61M 15/0021A61M 15/0086A61M 15/0008A61M 11/006A61M 15/009A61M 15/0065
46
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Claims

Abstract

A delivery device for delivering a metered amount of substance (L) in response to exhalation by a user, the delivery device comprising: a mouthpiece ( 5 ) through which the user in use exhales; an outlet ( 45 ) from which substance Is delivered; and a dispensing unit ( 35 ) which is operable to dispense a metered amount of substance through the outlet in response to exhalation by the user through the mouthpiece, wherein the dispensing unit comprises a body member ( 37 ) which includes a cavity ( 39 ) for containing a metered amount of substance, an outlet nozzle ( 43 ) which is fluidly connected to the cavity from which substance is in use delivered, and a dispensing ( 41 ) member which is movably disposed in the cavity and configured to be driven through the cavity by a driving pressure created by exhalation of the user, such as to cause substance to be delivered from the outlet nozzle.

Claims

exact text as granted — not AI-modified
1 . A delivery device for delivering a metered amount of substance in response to exhalation by a user, the delivery device comprising:
 a mouthpiece through which the user in use exhales;   an outlet from which substance is delivered; and   a dispensing unit which is operable to dispense a metered amount of substance through the outlet in response to exhalation by the user through the mouthpiece, wherein the dispensing unit comprises a body member which includes a cavity for containing a metered amount of substance, an outlet nozzle which is fluidly connected to the cavity from which substance is in use delivered, and a dispensing member which is movably disposed in the cavity and configured to be driven through the cavity by a driving pressure created by exhalation of the user, such as to cause substance to be delivered from the outlet nozzle.   
     
     
         2 . The delivery device of  claim 1 , wherein the cavity is an elongate cavity. 
     
     
         3 . The delivery device of  claim 2 , wherein the cavity has a cylindrical section and the dispensing member comprises a ball which is moved along the cavity by the driving pressure created by exhalation of the user. 
     
     
         4 . The delivery device of  claim 3 , wherein the ball sealingly engages with an inner peripheral wall of the cavity. 
     
     
         5 . The delivery device of any of  claims 1  to  4 , wherein the cavity and the dispensing member are configured to provide for movement of the dispensing member at a driving pressure of less than about 5 kPa, and preferably less than about 3 kPa. 
     
     
         6 . The delivery device of any of  claims 1  to  5 , wherein the outlet nozzle provides for an aerosol spray. 
     
     
         7 . The delivery device of  claim 6 , wherein the outlet nozzle provides for a substantially rectilinear flow for a distance of at least about 15 mm, preferably at least about 20 mm, more preferably at least about 25 mm and yet more preferably at least about 30 mm from exit of the outlet nozzle. 
     
     
         8 . The delivery device of any of  claims 1  to  5 , wherein the outlet nozzle provides for a jet. 
     
     
         9 . The delivery device of any of  claims 1  to  8 , further comprising:
 a pressure regulator which is fluidly connected to the dispensing unit, such as to provide for application of a predeterminable driving pressure to the dispensing member. 
 
     
     
         10 . The delivery device of any of  claims 1  to  9 , wherein the mouthpiece and the outlet are fluidly connected, such as to provide for an air flow through the outlet on exhalation by the user through the mouthpiece. 
     
     
         11 . The delivery device of  claim 10 , further comprising:
 a housing in which the dispensing unit is disposed and to which the mouthpiece and the nosepiece are fluidly connected, such as to define a fluid communication path therebetween.   
     
     
         12 . The delivery device of  claim 11 , further comprising:
 a baffle member which is disposed in the fluid communication path.   
     
     
         13 . The delivery device of  claim 12 , wherein the baffle member includes a first, driving air pressure channel which is fluidly connected to the dispensing unit and at which the driving pressure is created on exhalation by the user to actuate the dispensing unit, and at least one second, entraining air flow channel through which an entraining air flow is delivered for entraining substance as delivered by the dispensing unit. 
     
     
         14 . The delivery device of  claim 13 , wherein the baffle member includes a plurality of entraining air flow channels. 
     
     
         15 . The delivery device of any of  claims 12  to  14 , wherein the housing includes an inlet chamber upstream of the baffle member which flares outwardly from the mouthpiece. 
     
     
         16 . The delivery device of any of  claims 12  to  15 , wherein the housing includes an outlet chamber downstream of the baffle member. 
     
     
         17 . The delivery device of  claim 16 , wherein the outlet chamber surrounds the dispensing unit. 
     
     
         18 . The delivery device of any of  claims 10  to  17 , wherein the outlet includes a flow restrictor for providing a flow restriction thereat. 
     
     
         19 . The delivery device of  claim 18 , wherein the flow restrictor tapers inwardly in a flow direction from the mouthpiece to the nosepiece. 
     
     
         20 . The delivery device of  claim 19 , wherein the flow restrictor has a frusto-conical section. 
     
     
         21 . The delivery device of any of  claims 10  to  20 , further comprising:
 a flow regulator which is disposed at the outlet nozzle of the dispensing unit. 
 
     
     
         22 . The delivery device of  claim 21 , wherein the flow regulator includes a plurality of flow apertures which are located on an annulus surrounding the outlet nozzle. 
     
     
         23 . The delivery device of any of  claims 1  to  22 , where configured to deliver a liquid. 
     
     
         24 . The delivery device of any of  claims 1  to  23 , wherein the outlet is a nosepiece and the delivery device is a nasal delivery device for delivering substance to a nasal airway of a subject. 
     
     
         25 . A delivery device substantially as hereinbefore described with reference to the accompanying drawings.

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