Antimicrobial and foamable alcoholic compositions

Abstract

Antimicrobial and foamable alcoholic compositions, where the compositions include at least about 40 wt. % of a C 1-4 alcohol and one or more silane surfactants selected from (1) zwitterionic silane surfactants, (2) polyalkoxylated silane surfactants that contain at least one silane group and at least one polyalkylene oxide chain.

1 . An antimicrobial alcoholic composition comprising:
 at least about 40 weight percent of a C 1-4  alcohol or a mixture of two or more C 1-9  alcohols, based upon the total weight of the alcoholic composition; and   one or more silane surfactants selected from (1) zwitterionic silane surfactants, (2) polyalkoxylated silane surfactants that contain at least one silane group and at least one polyalkylene oxide chain, and that are characterized by having a molecular weight distribution of less than about 2.4.   
     
     
         2 . The composition of  claim 1 , wherein said alcohol comprises methanol, ethanol, propanol, isopropanol, butanol, isobutanol, tertiary butanol, or mixtures thereof. 
     
     
         3 . The composition of  claim 1 , wherein said zwitterionic silane surfactant includes a polar ionic portion and a non-polar silane portion. 
     
     
         4 . The composition of  claim 1 , wherein the zwitterionic surfactant may be represented by the formula 
       
         
           
           
               
               
           
         
       
       where wherein R 1 , R 2 , and R 3  are each independently a branched or linear C 2  to C 20  hydrocarbon group, R 7  is a divalent hydrocarbon group with about 4 to about 20 carbon atoms and optionally includes one or both of a lateral hydroxyl group and an ether oxygen, and R 9  is selected from the group consisting of 
       
         
           
           
               
               
           
         
       
       where R 4 , R 5  and R 8  are each independently alkyl groups with from 1 to about 6 carbon atoms. 
     
     
         5 . The composition of  claim 1 , wherein said zwitterionic silane surfactant includes a polar dimethylglycine portion and a non-polar silane portion. 
     
     
         6 . The composition of  claim 1 , wherein the zwitterionic surfactant may be represented by the formula 
       
         
           
           
               
               
           
         
       
       where each R is independently a branched or linear C 2  to C 20  hydrocarbon group, and wherein n is an integer from 1 to about 20. 
     
     
         7 . The composition of  claim 1 , wherein said zwitterionic silane surfactant is represented by the formula 
       
         
           
           
               
               
           
         
       
       where n is an integer from 1 to about 20. 
     
     
         8 . The composition of  claim 1 , wherein said composition further comprises at least one foam enhancer. 
     
     
         9 . The composition of  claim 1 , wherein said silane surfactant is bis-PEG-18 methyl ether dimethyl silane. 
     
     
         10 . The composition of  claim 1 , wherein the composition comprises at least about 50 wt. % of a C 1-4  alcohol, based upon the total weight of the alcoholic composition; and from about 0.001 to about 10 wt. % of one or more silane surfactants. 
     
     
         11 . The composition of  claim 1 , wherein the composition comprises from about 0.001 to about 20 wt. % of one or more silane surfactants. 
     
     
         12 . The composition of  claim 1 , wherein the molecular weight distribution (Mw/Mn) of the silane surfactant is less than about 2.2. 
     
     
         13 . The composition of  claim 1 , wherein the molecular weight distribution (Mw/Mn) of the silane surfactant is less than about 2.0. 
     
     
         14 . The composition of  claim 1 , wherein the molecular weight distribution (Mw/Mn) of the silane surfactant is less than about 1.8. 
     
     
         15 . The composition of  claim 1 , wherein the composition comprises a primary foam enhancer that includes a poly(ethylene oxide)polymer, a poloxamer, hydroxyethyl cellulose, hydroxypropyl cellulose, or a combination thereof. 
     
     
         16 . The composition of  claim 1 , wherein the composition comprises from 0 to about 10 wt. % of a primary foam enhancer that includes a poly(ethylene oxide)polymer, a poloxamer, hydroxyethyl cellulose, hydroxypropyl cellulose, or a combination thereof, based upon the total weight of the composition. 
     
     
         17 . A method of preparing a zwitterionic surfactant, the method comprising the steps of:
 reacting an epoxide by means of an addition reaction in the presence of a hydrosilylation catalyst with a silane of the general formula   
       
         
           
           
               
               
           
         
       
       to form a silane-modified epoxide having an epoxide ring; and
 reacting the silane-modified epoxide with an amine compound of the general formula 
 
       
         
           
           
               
               
           
         
       
       to form a betaine of the general formula 
       
         
           
           
               
               
           
         
       
       wherein R 1 , R 2 , and R 3  are each independently a branched or linear C 2  to C 20  hydrocarbon group, R 7  derives from the epoxide, and is a divalent hydrocarbon group with about 4 to about 20 carbon atoms and optionally includes a lateral hydroxyl group, and optionally includes an ether oxygen, and R 4  and R 5  are each independently selected from alkyl groups with 1 to about 6 carbon atoms. 
     
     
         18 . The method of  claim 17 , wherein R 1 , R 2 , and R 3  are each n-butyl.